海外医薬品不足情報｜医薬政策企画 P-Cubed

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2025.11.10 [ ドイツ ]

BfArMボトルネック・レポート（2025年11月3日～11月9日）

Active ingredients

Message type

Date of last message

Type of reason

AM designation

Darifenacin hydrobromide

Initial report

07.11.2025

Other

Darifenacin Aristo 15 mg prolonged-release tablets

Tolterodine tartrate

Initial report

07.11.2025

Other

Tolterodine Aristo 1 mg film-coated tablets

Tolterodine tartrate

Initial report

07.11.2025

Other

Tolterodine-Aristo 2 mg film-coated tablets

Posaconazole

Change notification

07.11.2025

Other

Posaconazole HEXAL 40 mg/ml oral suspension

Tolterodine tartrate

Initial report

07.11.2025

Other

Detrusitol 1 mg film-coated tablets

Beclomethasone dipropionate (Ph.Eur.)

Change notification

07.11.2025

Other

Beclorhinol aquosum 50 micrograms

Paliperidone palmitate

Change notification

06.11.2025

Other

XEPLION 25 mg prolonged-release suspension for injection – OP1ml

Rifampicin sodium

Change notification

06.11.2025

Other

Eremfat i.v. 600mg

Nitrendipine

Initial report

06.11.2025

Other

Nitrendipine AL 10

Urapidil

Initial report

06.11.2025

Other

Urapidil AL 90 mg hard capsules, delayed release

Urapidil

Initial report

06.11.2025

Other

Urapidil AL 30 mg hard capsules, delayed release

Imiquimod

Change notification

06.11.2025

Production problem

Aldara 5% cream – OP24

Calcium folinate hydrate

Change notification

06.11.2025

Production problem

Calcium folinate onkovis 10 mg/ml solution for injection

Quetiapine fumarate (Ph.Eur.)

Change notification

06.11.2025

Other

Quetiapine AL 100 mg film-coated tablets

Salbutamol sulfate

Initial report

05.11.2025

Other

Bronchospray Autohaler

Imiquimod

Change notification

05.11.2025

Production problem

Imikeraderm 50 mg/g cream

Sodium mycophenolate

Initial report

05.11.2025

Other

Mycophenolic acid HEXAL 180 mg gastro-resistant tablets

Sodium mycophenolate

Change notification

05.11.2025

Other

Mycophenolic acid HEXAL 360 mg gastro-resistant tablets

Sitagliptin hydrochloride monohydrate

Change notification

05.11.2025

Production problem

Sitagliptin PUREN 50 mg film-coated tablets

Nimodipine

Change notification

05.11.2025

Other

Nimodipine Hexal 30 mg

Propranolol hydrochloride

Initial report

05.11.2025

Other

Propra-ratiopharm 40 mg film-coated tablets

Propranolol hydrochloride

Initial report

05.11.2025

Other

Propra-ratiopharm 10 mg film-coated tablets

Dexamethasone dihydrogen phosphate disodium (Ph.Eur.)

Initial report

05.11.2025

Other

Dexa-ratiopharm 4 mg solution for injection

Ipratropium bromide (Ph.Eur.)

Change notification

05.11.2025

Production problem

Ipratropium Teva 250 micrograms/1 ml solution for nebulizer

Buprenorphine

Change notification

05.11.2025

Other

Buprenorphine AWD Matrix 52.5 micrograms/h Transdermal patch

Buprenorphine

Change notification

05.11.2025

Other

Buprenorphine AWD Matrix 70 micrograms/h Transdermal patch

Methylphenidate hydrochloride

Change notification

05.11.2025

Other

Methylphenidate-ratiopharm 10 mg modified-release hard capsules

Galantamine hydrobromide

Change notification

05.11.2025

Other

Galantamine-ratiopharm 8 mg hard capsules, delayed release

Carbamazepine

Change notification

05.11.2025

Other

Carbamazepine-ratiopharm 200 mg prolonged-release tablets

Buprenorphine

Change notification

05.11.2025

Other

Buprenorphine-ratiopharm 70 micrograms/h transdermal patch

Buprenorphine

Change notification

05.11.2025

Other

Buprenorphine-ratiopharm 52.5 micrograms/h Transdermal patch

Buprenorphine

Change notification

05.11.2025

Other

Buprenorphine-ratiopharm 35 micrograms/h transdermal patch

Alprazolam

Change notification

05.11.2025

Other

Alprazolam-ratiopharm 1.0 mg tablets

Methylphenidate hydrochloride

Change notification

05.11.2025

Other

Methylphenidate-ratiopharm 40 mg modified-release hard capsules

Doxepine hydrochloride (Ph.Eur.)

Change notification

04.11.2025

Production problem

Doxepin 25 Holsten

Doxepine hydrochloride (Ph.Eur.)

Change notification

04.11.2025

Other

Doxepin 50 Holsten

Doxepine hydrochloride (Ph.Eur.)

Change notification

04.11.2025

Production problem

Doxepin 75 Holsten

Gabapentin

Change notification

04.11.2025

Other

Gabapentin Holsten 300 mg hard capsules

Gabapentin

Change notification

04.11.2025

Production problem

Gabapentin Holsten 600 mg film-coated tablets

Gabapentin

Change notification

04.11.2025

Other

Gabapentin Holsten 800 mg film-coated tablets

Mercaptopurine

Change notification

04.11.2025

Other

Mercaptopurine Holsten 50 mg tablets

Levetiracetam

Change notification

04.11.2025

Other

Levetiracetam Holsten 250 mg film-coated tablets

Ipratropium bromide (Ph.Eur.); salbutamol sulfate

Change notification

04.11.2025

Production problem

COMBIPRASAL 0.5 mg / 2.5 mg solution for nebulizer

Ipratropium bromide

Change notification

04.11.2025

Production problem

Ipratropium bromide 250 micrograms / 1 ml Stulln

Levetiracetam

Initial report

04.11.2025

Other

Levetiracetam Holsten 750 mg film-coated tablets

Amlodipine besylate; hydrochlorothiazide; valsartan

Initial report

04.11.2025

Other

Amlodipine/Valsartan/HCT Holsten 5 mg/160 mg/12.5 mg film-coated tablets

Docetaxel

Initial report

04.11.2025

Production problem

Docetaxel Aurobindo 20 mg/ml concentrate for solution for infusion

Venlafaxine hydrochloride

Initial report

04.11.2025

Other

Venlafaxine Aurobindo 75 mg hard capsule, delayed release

Topiramate

Initial report

04.11.2025

Other

Topiramate PUREN 50 mg film-coated tablets

Tranexamic acid

Initial report

04.11.2025

Production problem

Tranexamic acid PUREN 100 mg/ml solution for injection

Duloxetine hydrochloride

Initial report

04.11.2025

Other

Duloxetine PUREN 60 mg gastro-resistant hard capsules

Anastrozole

Initial report

04.11.2025

Production problem

AnastroPUREN 1 mg film-coated tablets

Duloxetine hydrochloride

Initial report

04.11.2025

Other

Duloxetine PUREN 30 mg gastro-resistant hard capsules

Quetiapine fumarate (Ph.Eur.)

Change notification

04.11.2025

Other

Seroquel Prolong 200 mg prolonged-release tablets

Insulin lispro

Initial report

04.11.2025

Other

Humalog KwikPen 100 E/ml solution for injection – OP (5x3ml)

Olanzapine

Change notification

04.11.2025

Production problem

ZYPREXA

Ipratropium bromide (Ph.Eur.); salbutamol sulfate

Initial report

04.11.2025

Other

Ipratropium/salbutamol Cipla 0.5 mg/2.5 mg solution for nebulizer

Cefazolin sodium

Initial report

04.11.2025

Production problem

Cefazolin Hikma 2 g powder for solution for injection/infusion

Amiodarone hydrochloride

Initial report

04.11.2025

Other

Amiodarone PUREN 200 mg tablets

Atorvastatin calcium trihydrate (Ph.Eur.)

Initial report

04.11.2025

Other

Atorvastatin PUREN 80 mg film-coated tablets

Atorvastatin calcium trihydrate (Ph.Eur.)

Change notification

04.11.2025

Other

Atorvastatin PUREN 20 mg film-coated tablets

Methylphenidate hydrochloride

Change notification

04.11.2025

Other

Methylphenidate hydrochloride HEXAL 36 mg prolonged-release tablets

Atomoxetine hydrochloride

Change notification

04.11.2025

Other

Atomoxe – 1 A Pharma 100 mg hard capsules

Topiramate

Change notification

04.11.2025

Production problem

Topiramate PUREN 100 mg film-coated tablets

Atomoxetine hydrochloride

Change notification

04.11.2025

Other

Atomoxe – 1 A Pharma 18 mg hard capsules

Atomoxetine hydrochloride

Change notification

04.11.2025

Other

Atomoxe – 1 A Pharma 25 mg hard capsules

Atomoxetine hydrochloride

Change notification

04.11.2025

Other

Atomoxe – 1 A Pharma 40 mg hard capsules

Quetiapine fumarate (Ph.Eur.)

Change notification

04.11.2025

Other

Seroquel Prolong 400 mg prolonged-release tablets

Atomoxetine hydrochloride

Change notification

04.11.2025

Other

Atomoxe – 1 A Pharma 60 mg hard capsules

Atomoxetine hydrochloride

Change notification

04.11.2025

Other

Atomoxe – 1 A Pharma 80 mg hard capsules

Urapidil

Change notification

04.11.2025

Production problem

Urapidil Bluefish 30 mg hard capsules, delayed release

Urapidil

Change notification

04.11.2025

Production problem

Urapidil Bluefish 90 mg hard capsules, delayed release

Quetiapine fumarate (Ph.Eur.)

Initial report

04.11.2025

Other

Seroquel Prolong 150 mg prolonged-release tablets

Aprepitant

Initial report

03.11.2025

Production problem

Aprepitant Zentiva 80 mg hard capsules

Aprepitant

Initial report

03.11.2025

Production problem

Aprepitant Zentiva 125 mg hard capsules

Aprepitant

Change notification

03.11.2025

Production problem

Aprepitant Zentiva 80 mg and 125 mg hard capsules

Dimenhydrinate

Initial report

03.11.2025

Production problem

Dimenhydrinate PANPHARMA 6.2 mg/ml solution for injection (i.v.)

Zonisamide

Initial report

03.11.2025

Production problem

Zonisamide Glenmark 100 mg hard capsules

Anastrozole

Change notification

03.11.2025

Other

Anastrozole Denk 1 mg film-coated tablets

Perindopril tert-butylamine

Initial report

03.11.2025

Other

Perindopril Erbumine Glenmark 4 mg tablets

Riluzole

Initial report

03.11.2025

Other

Glentek 50 mg film-coated tablets

Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y)

Change notification

03.11.2025

Other

Ferrlecit 62.5 mg

Clonidine hydrochloride

Change notification

03.11.2025

Other

Clonidine-ratiopharm 75

Rizatriptan benzoate

Change notification

03.11.2025

Production problem

Rizatriptan Glenmark 5 mg tablets

Clonidine hydrochloride

Change notification

03.11.2025

Other

Clonidine-ratiopharm 150

Rizatriptan benzoate

Change notification

03.11.2025

Production problem

Rizatriptan Glenmark 5 mg orodispersible tablets

Clonidine hydrochloride

Change notification

03.11.2025

Other

Clonidine-ratiopharm 300

Rizatriptan benzoate

Change notification

03.11.2025

Production problem

Rizatriptan Glenmark 10 mg orodispersible tablets

Rizatriptan benzoate

Change notification

03.11.2025

Production problem

Rizatriptan Glenmark 10 mg tablets

Quetiapine fumarate (Ph.Eur.)

Change notification

03.11.2025

Production problem

Quetiapine Glenmark 200 mg prolonged-release tablets

Fusidic acid (Ph.Eur.)

Change notification

03.11.2025

Production problem

Fucithalmic 10 mg/g eye drops

Dexketoprofen trometamol

Change notification

03.11.2025

Production problem

Sympal inject 50 mg solution for injection/infusion

Hydrocortisone acetate (Ph.Eur.)

Change notification

03.11.2025

Production problem

Hydrocortisone-POS N 2.5%

Dexamethasone dihydrogen phosphate disodium (Ph.Eur.); gentamicin sulfate

Change notification

03.11.2025

Production problem

Dexa-Gentamicin

Prednisolone acetate

Change notification

03.11.2025

Production problem

Predni-POS 1%

Aciclovir

Change notification

03.11.2025

Production problem

Virupos

Fluorometholone

Change notification

03.11.2025

Production problem

Fluoropos

Gentamicin sulfate

Change notification

03.11.2025

Production problem

Gentamicin-POS

Phenylephrine hydrochloride

Change notification

03.11.2025

Production problem

Neosynephrine-POS 5%

2025.11.10 [ フランス ]

ANSMフランス供給不足情報（2025年11月3日～11月9日）

Active ingredients	Status	Update	Specialty
diltiazem (hydrochloride)	Supply tension	07/11/2025	Tildiem 25 mg, powder and solution for intravenous injection
tolvaptan	Supply tension	07/11/2025	Tolvaptan Biogaran 30 mg, tablet + Tolvaptan Biogaran 60 mg, tablet
urokinase	Return to availability	07/11/2025	Thérasolv 250,000 IU, powder for solution for injection/infusion
diltiazem (hydrochloride)	Marketing discontinuation	07/11/2025	Tildiem 100 mg, powder for solution for injection (IV)
chlorpromazine (hydrochloride)	Stock shortage	07/11/2025	Largactil 100 mg, film-coated tablet
pertuzumab/trastuzumab	Return to availability	07/11/2025	Phesgo 1200 mg/600 mg, solution for injection
clomipramine (hydrochloride)	Supply tension	06/11/2025	Clomipramine Viatris 25 mg, film-coated tablet
ornidazole	Return to availability	05/11/2025	Tiberal 500 mg, solution for infusion
cyamemazine	Stock shortage	03/11/2025	Tercian 50 mg/5 mL, injectable solution in ampoule

2025.11.10 [ オーストラリア ]

TGAオーストラリア供給不足情報（2025年11月3日～11月9日）

Active ingredients	Dosage form	Quantity of active ingredients	Shortage status	Availability	Reason	Last updated
betiatide	Injection, powder for	1 mg	Current	Emergency Supply Only	Manufacturing	7/11/2025
tobramycin	Injection, solution	80 mg	Anticipated	Available	Manufacturing	7/11/2025
primidone	Tablet, uncoated	250 mg	Current	Emergency Supply Only	Manufacturing	7/11/2025
trandolapril	Capsule	2 mg	Current	Unavailable	Unexpected increase in demand due to other sponsors unable to supply	7/11/2025
topiramate	Tablet, film coated	25 mg	Current	Unavailable	Manufacturing	7/11/2025
sodium lactate~magnesium chloride hexahydrate~glucose~sodium chloride~calcium chloride dihydrate	Solution, irrigation	4.48 g/L~50.8 mg/L~15 g/L~5.38 g/L~183 mg/L	Resolved	Available	Manufacturing	7/11/2025
glucose~sodium chloride~sodium lactate~magnesium chloride hexahydrate~calcium chloride dihydrate	Solution, irrigation	25 g/L~5.38 g/L~4.48 g/L~50.8 mg/L~183 mg/L	Resolved	Available	Manufacturing	7/11/2025
pramipexole dihydrochloride monohydrate	Tablet	.125 mg	Current	Unavailable	Manufacturing	7/11/2025
pramipexole dihydrochloride monohydrate	Tablet	.25 mg	Current	Unavailable	Manufacturing	7/11/2025
ondansetron hydrochloride dihydrate	Tablet, film coated	4.986 mg	Anticipated	Available	Manufacturing	7/11/2025
atorvastatin calcium trihydrate	Tablet, film coated	43.38 mg	Current	Unavailable	Manufacturing	7/11/2025
galantamine hydrobromide	Capsule, modified release	20.504 mg	Current	Unavailable	Manufacturing	7/11/2025
galantamine hydrobromide	Capsule, modified release	30.756 mg	Current	Unavailable	Manufacturing	7/11/2025
sumatriptan succinate	Tablet, film coated	69.99 mg	Current	Limited Availability	Manufacturing	7/11/2025
phenobarbital	Tablet, uncoated	30 mg	Current	Unavailable	Manufacturing	7/11/2025
carbidopa monohydrate~entacapone~levodopa	Tablet, film coated	27 mg~200 mg~100 mg	Current	Limited Availability	Unexpected increase in consumer demand	7/11/2025
levodopa~carbidopa monohydrate~entacapone	Tablet, film coated	150 mg~40.5 mg~200 mg	Current	Unavailable	Unexpected increase in consumer demand	7/11/2025
levodopa~carbidopa monohydrate~entacapone	Tablet, film coated	200 mg~54.1 mg~200 mg	Current	Limited Availability	Unexpected increase in consumer demand	7/11/2025
ezetimibe	Tablet, uncoated	10 mg	Current	Limited Availability	Unexpected increase in consumer demand	7/11/2025
ezetimibe	Tablet, uncoated	10 mg	Current	Unavailable	Unexpected increase in consumer demand	7/11/2025
mebeverine hydrochloride	Tablet, film coated	135 mg	Current	Limited Availability	Manufacturing	7/11/2025
latanoprost	Eye Drops, solution	.05 mg/mL	Anticipated	Available	Manufacturing	7/11/2025
metaraminol tartrate	Injection, solution	19 mg	Current	Unavailable	Unexpected increase in demand due to other sponsors unable to supply	7/11/2025
aprepitant	Capsule	165 mg	Anticipated	Available	Manufacturing	7/11/2025
fingolimod hydrochloride	Capsule	560 microgram	Anticipated	Available	Manufacturing	7/11/2025
lamotrigine	Tablet, chewable	100 mg	Current	Unavailable	Manufacturing	7/11/2025
valsartan~sacubitril	Tablet, film coated	51.4 mg~48.6 mg	Current	Unavailable	Manufacturing	7/11/2025
sacubitril~valsartan	Tablet, film coated	24.3 mg~25.7 mg	Current	Unavailable	Manufacturing	7/11/2025
sitagliptin hydrochloride monohydrate~metformin hydrochloride	Tablet, modified release	56.685 mg~1000 mg	Current	Limited Availability	Manufacturing	7/11/2025
nitrofurantoin	Capsule, hard	50 mg	Anticipated	Available	Manufacturing	7/11/2025
naltrexone hydrochloride	Tablet, film coated	50 mg	Anticipated	Available	Manufacturing	7/11/2025
rivaroxaban	Tablet, film coated	10 mg	Resolved	Available	Manufacturing	7/11/2025
carbidopa monohydrate~levodopa	Tablet, uncoated	26.9 mg~100 mg	Resolved	Available	Manufacturing	7/11/2025
bumetanide	Tablet, uncoated	1 mg	Current	Limited Availability	Manufacturing	7/11/2025
diltiazem hydrochloride	Capsule, modified release	360 mg	Current	Limited Availability	Manufacturing	7/11/2025
magnesium chloride hexahydrate~calcium chloride dihydrate~sodium lactate~sodium chloride~icodextrin	Solution, dialysis	51 mg/L~257 mg/L~4.5 g/L~5.4 g/L~75 g/L	Resolved	Available	Manufacturing	7/11/2025
nizatidine	Capsule, hard	300 mg	Anticipated	Available	Manufacturing	7/11/2025
galantamine hydrobromide~galantamine	Capsule, modified release	20.51 mg~16 mg	Current	Limited Availability	Unexpected increase in demand due to other sponsors unable to supply	7/11/2025
lamotrigine	Tablet, dispersible	200 mg	Current	Limited Availability	Manufacturing	7/11/2025
sodium amidotrizoate~amidotrizoate meglumine	Oral Liquid, solution	100 mg/mL~660 mg/mL	Discontinued	Unavailable	Seasonal depletion of stock	6/11/2025
live varicella vaccine	Injection, powder for	2700 PFU/mL	Current	Limited Availability	Unexpected increase in demand due to other sponsors unable to supply	6/11/2025
minoxidil	Tablet, uncoated	10 mg	Anticipated	Available	Manufacturing	6/11/2025
ropivacaine hydrochloride	Injection, solution	75 mg	Anticipated	Available	Transport / Logistic issues / Storage capacity issues	6/11/2025
Infliximab	Injection, powder for	100 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	6/11/2025
montelukast sodium	Tablet, chewable	4.16 mg	Current	Limited Availability	Unexpected increase in demand due to other sponsors unable to supply	6/11/2025
montelukast sodium	Tablet, chewable	4.16 mg	Current	Unavailable	Manufacturing	6/11/2025
verapamil hydrochloride	Tablet, modified release	240 mg	Current	Limited Availability	Manufacturing	5/11/2025
terbutaline sulfate	Injection, solution	.5 mg/mL	Anticipated	Available	Manufacturing	5/11/2025
midazolam	Injection, solution	5 mg/mL	Resolved	Available	Manufacturing	5/11/2025
pantoprazole sodium sesquihydrate	Tablet, enteric coated	45.4 mg	Resolved	Available	Unexpected increase in consumer demand	5/11/2025
Alteplase	Injection, powder for	50 mg	Current	Limited Availability	Unexpected increase in consumer demand	5/11/2025
montelukast sodium	Tablet, chewable	5.2 mg	Resolved	Available	Manufacturing	5/11/2025
montelukast sodium	Tablet, chewable	4.16 mg	Current	Unavailable	Manufacturing	5/11/2025
amlodipine besilate~atorvastatin calcium trihydrate	Tablet, film coated	13.88 mg~10.844 mg	Current	Unavailable	Manufacturing	5/11/2025
mesalazine	Granules, modified release	4 g	Current	Limited Availability	Transport / Logistic issues / Storage capacity issues	5/11/2025
dabigatran etexilate mesilate	Capsule, hard	172.95 mg	Current	Unavailable	Manufacturing	5/11/2025
doxepin hydrochloride	Capsule, hard	11.3 mg	Anticipated	Available	Manufacturing	5/11/2025
midodrine hydrochloride	Tablet	5 mg	Current	Unavailable	Manufacturing	5/11/2025
larotrectinib sulfate	Capsule, hard	30.7 mg	Resolved	Available	Unexpected increase in consumer demand	5/11/2025
tenofovir disoproxil succinate~emtricitabine	Tablet, film coated	300.6 mg~200 mg	Current	Unavailable	Manufacturing	5/11/2025
flecainide acetate	Tablet	50 mg	Current	Unavailable	Manufacturing	5/11/2025
rivaroxaban	Tablet, film coated	10 mg	Anticipated	Available	Manufacturing	5/11/2025
rivaroxaban	Tablet, film coated	15 mg	Anticipated	Available	Manufacturing	5/11/2025
furosemide	Injection, solution	20 mg	Resolved	Available	Manufacturing	5/11/2025
ethinylestradiol~norethisterone	Tablet, uncoated	36 microgram~500 microgram	Current	Limited Availability	Manufacturing	5/11/2025
Alteplase	Diluent, not applicable	10 mg	Current	Limited Availability	Unexpected increase in consumer demand	5/11/2025
fluorouracil	Injection, solution	50 mg/mL	Resolved	Available	Unexpected increase in consumer demand	5/11/2025
flunitrazepam	Tablet, film coated	1 mg	Anticipated	Available	Manufacturing	5/11/2025
indometacin	Suppository, moulded	100 mg	Current	Unavailable	Manufacturing	4/11/2025
ropivacaine hydrochloride	Injection, solution	10 mg/mL	Current	Unavailable	Unexpected increase in demand due to other sponsors unable to supply	4/11/2025
ropivacaine hydrochloride	Injection, solution	7.5 mg/mL	Current	Unavailable	Unexpected increase in demand due to other sponsors unable to supply	4/11/2025
alfentanil hydrochloride	Injection, solution	1.0876 mg	Resolved	Available	Transport / Logistic issues / Storage capacity issues	4/11/2025
nystatin	Oral Liquid, suspension	100000 IU/mL	Current	Unavailable	Unexpected increase in consumer demand	4/11/2025
pregabalin	Capsule, hard	25 mg	Current	Unavailable	Manufacturing	4/11/2025
escitalopram oxalate	Tablet, film coated	12.74 mg	Current	Unavailable	Commercial Changes / Commercial viability	4/11/2025
escitalopram oxalate	Tablet, film coated	25.47 mg	Current	Limited Availability	Manufacturing	4/11/2025
lacosamide	Tablet, film coated	150 mg	Current	Limited Availability	Manufacturing	4/11/2025
montelukast sodium	Tablet, chewable	5.2 mg	Current	Unavailable	Manufacturing	4/11/2025
levothyroxine sodium	Tablet, uncoated	.05 mg	Current	Limited Availability	Manufacturing	4/11/2025
ramipril	Tablet, uncoated	1.25 mg	Resolved	Available	Transport / Logistic issues / Storage capacity issues	4/11/2025
ramipril	Tablet, uncoated	2.5 mg	Current	Limited Availability	Manufacturing	4/11/2025
ropivacaine hydrochloride	Injection, solution	7.5 mg/mL	Current	Limited Availability	Manufacturing	4/11/2025
ropivacaine hydrochloride	Injection, solution	7.5 mg/mL	Current	Unavailable	Manufacturing	4/11/2025
sertraline hydrochloride	Tablet, film coated	55.96 mg	Current	Unavailable	Manufacturing	3/11/2025
clozapine	Oral Liquid, suspension	50 mg/mL	Current	Unavailable	Manufacturing	3/11/2025
risperidone	Tablet	1 mg	Current	Unavailable	Unexpected increase in demand due to other sponsors unable to supply	3/11/2025
lamivudine	Tablet, film coated	300 mg	Anticipated	Available	Manufacturing	3/11/2025
pramipexole dihydrochloride monohydrate	Tablet	1 mg	Anticipated	Available	Manufacturing	3/11/2025
olanzapine	Tablet, orally disintegrating	10 mg	Resolved	Available	Manufacturing	3/11/2025
montelukast sodium	Tablet, chewable	4.16 mg	Current	Unavailable	Manufacturing	3/11/2025
finasteride	Tablet, film coated	5 mg	Current	Limited Availability	Manufacturing	3/11/2025
risperidone	Tablet, film coated	.5 mg	Resolved	Available	Manufacturing	3/11/2025
entecavir	Tablet, film coated	1 mg	Anticipated	Available	Manufacturing	3/11/2025
primaquine phosphate	Tablet, uncoated	13.2 mg	Current	Emergency Supply Only	Manufacturing	3/11/2025
pramipexole dihydrochloride monohydrate	Tablet	1 mg	Anticipated	Available	Manufacturing	3/11/2025
nicorandil	Tablet, uncoated	20 mg	Anticipated	Available	Manufacturing	3/11/2025
tobramycin	Inhalation, conventional	60 mg/mL	Anticipated	Available	Manufacturing	3/11/2025
phenytoin sodium	Capsule, hard	30 mg	Resolved	Available	Manufacturing	3/11/2025
bendamustine hydrochloride	Injection, powder for	25 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	3/11/2025
finasteride	Tablet, film coated	1 mg	Anticipated	Available	Manufacturing	3/11/2025
Tocilizumab	Injection, solution	162 mg	Anticipated	Available	Manufacturing	3/11/2025
bleomycin sulfate	Injection, powder for	15000 IU	Anticipated	Available	Manufacturing	3/11/2025
pramipexole dihydrochloride monohydrate	Tablet, uncoated	1 mg	Anticipated	Available	Unexpected increase in demand due to other sponsors unable to supply	3/11/2025
pramipexole dihydrochloride monohydrate	Tablet, uncoated	.125 mg	Anticipated	Available	Unexpected increase in demand due to other sponsors unable to supply	3/11/2025

2025.11.10 [ 米国 ]

ASHP供給不足情報（2025年11月3日～11月9日）

Generic Name	Shortage Status	Revision Date
Ephedrine Injection	Current Shortages	7-Nov-25
Methylphenidate Transdermal System	Current Shortages	7-Nov-25
Oseltamivir Oral Suspension and Capsules	Current Shortages	7-Nov-25
Pimecrolimus 1% Topical Cream	Current Shortages	7-Nov-25
Potassium Iodide and Iodine (Lugol’s Solution or Strong Iodine Solution) 14 mL bottles	Resolved Shortages	7-Nov-25
Rocuronium Injection	Current Shortages	7-Nov-25
Chlorothiazide Sodium Injection	Current Shortages	6-Nov-25
Dexamethasone Sodium Phosphate Injection	Current Shortages	6-Nov-25
Hydrocortisone Sodium Succinate Injection	Current Shortages	6-Nov-25
Ibrexafungerp Tablets	Current Shortages	6-Nov-25
Meperidine Hydrochloride Injection	Current Shortages	6-Nov-25
Mometasone Furoate Aerosol for Oral Inhalation	Current Shortages	6-Nov-25
Mometasone Furoate and Formoterol Fumarate Inhalation Aerosol	Current Shortages	6-Nov-25
Nitroglycerin Injection	Current Shortages	6-Nov-25
Antivenin Latrodectus Mactans (Black Widow Spider Antivenin)	Current Shortages	5-Nov-25
Azithromycin Powder for Oral Suspension Packets	Discontinued Drugs	5-Nov-25
Insulin Aspart Injection	Current Shortages	5-Nov-25
Lidocaine 5% Transdermal Patch	Current Shortages	5-Nov-25
Penicillin V Potassium Oral Presentations	Current Shortages	5-Nov-25
Sodium Ferric Gluconate Complex	Current Shortages	5-Nov-25
Sucralfate Tablets	Resolved Shortages	5-Nov-25
Amphetamine Mixed Salts, Immediate-Release Tablets	Current Shortages	4-Nov-25
Chlorothiazide Oral Suspension	Current Shortages	4-Nov-25
Fludarabine Injection	Current Shortages	4-Nov-25
Hydromorphone Hydrochloride Injection	Current Shortages	4-Nov-25
Hydroxocobalamin Solution for Intramuscular Injection	Current Shortages	4-Nov-25
Iloprost Inhalation Solution (Ventavis)	Resolved Shortages	4-Nov-25
Morphine Injection	Current Shortages	4-Nov-25
Morphine Sulfate Extended-Release Tablets	Resolved Shortages	4-Nov-25
Oxacillin Sodium Injection	Current Shortages	4-Nov-25
Fentanyl Citrate Injection	Current Shortages	Nov 03, 2025
Idarubicin Injection	Current Shortages	Nov 03, 2025
Labetalol Injection	Current Shortages	Nov 03, 2025
Penicillin G Benzathine / Penicillin G Procaine	Current Shortages	Nov 03, 2025
Sufentanil Injection	Current Shortages	Nov 03, 2025

2025.11.10 [ 米国 ]
FDA供給不足情報：新規・更新（2025年11月3日～11月9日）
New
November 07, 2025
- Atropine Sulfate Injection (Discontinuation)
- Calcium Chloride Injection (Discontinuation)
- Deferiprone Tablet (Discontinuation)
- Dextrose Monohydrate 50% Injection (Discontinuation)
- Epinephrine Injection (Discontinuation)
- Ketamine Hydrochloride Injection (Discontinuation)
- Lidocaine Hydrochloride Injection (Discontinuation)
- Sodium Bicarbonate Injection (Discontinuation)
November 03, 2025
- Acetaminophen; Oxycodone Hydrochloride Tablet (Discontinuation)
- Atazanavir Sulfate; Cobicistat Tablet (Discontinuation)
- Everolimus Tablet (Discontinuation)
- Lasmiditan Succinate Tablet (Discontinuation)
- Scopolamine Transdermal System (Discontinuation)
Updated
November 07, 2025
- Atropine Sulfate Injection (Currently in Shortage)
- Dextrose Monohydrate 50% Injection (Currently in Shortage)
- Hydrocortisone Sodium Succinate Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Methylprednisolone Acetate Injection (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)
November 06, 2025
- Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tablet (Currently in Shortage)
- Azacitidine Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Methylphenidate Hydrochloride Tablet, Extended Release (Currently in Shortage)
- Remifentanil Hydrochloride Injection (Currently in Shortage)
November 05, 2025
- Carboplatin Injection (Currently in Shortage)
- Desmopressin Acetate Spray (Currently in Shortage)
- Epinephrine Bitartrate, Lidocaine Hydrochloride Injection (Currently in Shortage)
- Fentanyl Citrate Injection (Currently in Shortage)
- Hydromorphone Hydrochloride Injection (Currently in Shortage)
- Lidocaine Hydrochloride Injection (Currently in Shortage)
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Lorazepam Injection (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
- Rocuronium Bromide Injection (Currently in Shortage)
- Sterile Water Injection (Currently in Shortage)
November 04, 2025
- Azacitidine Injection (Currently in Shortage)
- Carboplatin Injection (Currently in Shortage)
- Furosemide Injection (Currently in Shortage)
- Methotrexate Sodium Injection (Currently in Shortage)
- Metronidazole Injection (Currently in Shortage)
- Morphine Sulfate Injection (Currently in Shortage)
November 03, 2025
- Lisdexamfetamine Dimesylate Capsule (Currently in Shortage)
- Sodium Bicarbonate Injection (Currently in Shortage)