


| Active ingredients |
| Date of last message | Type of reason | AM designation | |
| Quetiapine fumarate (Ph.Eur.) | Change notification | 23.01.2026 | Production problem | Quetiapine Glenmark 200 mg prolonged-release tablets | |
| Quetiapine fumarate (Ph.Eur.) | Change notification | 23.01.2026 | Production problem | Quetiapine Glenmark 400 mg prolonged-release tablets | |
| Quetiapine fumarate (Ph.Eur.) | Change notification | 23.01.2026 | Production problem | Quetiapine Glenmark 150 mg prolonged-release tablets | |
| Quetiapine fumarate (Ph.Eur.) | Change notification | 23.01.2026 | Production problem | Quetiapine Glenmark 300 mg prolonged-release tablets | |
| Rifampicin sodium | Change notification | 23.01.2026 | Other | Eremfat i.v. 300mg | |
| Ivermectin | Change notification | 23.01.2026 | Other | DRIPONIN 3 mg tablets | |
| Galantamine hydrobromide | Change notification | 23.01.2026 | Production problem | Galantamine Glenmark 8 mg hard capsules, delayed release | |
| Galantamine hydrobromide | Change notification | 23.01.2026 | Production problem | Galantamine Glenmark 24 mg hard capsules, delayed release | |
| Galantamine hydrobromide | Change notification | 23.01.2026 | Production problem | Galantamine Glenmark 16 mg hard capsules, delayed release | |
| Fibrinogen, human | Change notification | 23.01.2026 | Other | Fibryga | |
| Isoniazid | Initial report | 23.01.2026 | Other | Isozid 50 mg | |
| Mannitol (Ph.Eur.) | Change notification | 23.01.2026 | Other | Bronchitol 40 mg hard capsule with powder for inhalation – OP10(1×10) | |
| Dexketoprofen trometamol | Change notification | 23.01.2026 | Production problem | Sympal inject 50 mg solution for injection/infusion | |
| Valaciclovir hydrochloride | Initial report | 22.01.2026 | Other | Valaciclovir – 1A Pharma 500 mg film-coated tablets | |
| Valaciclovir hydrochloride | Initial report | 22.01.2026 | Other | Valaciclovir – 1A Pharma 1000 mg film-coated tablets | |
| Fluoxetine hydrochloride | Change notification | 22.01.2026 | Other | Fluoxetine Micro Labs 30 mg hard capsules | |
| Clomipramine hydrochloride | Change notification | 22.01.2026 | Production problem | Anafranil 75 mg retard | |
| Ropivacaine hydrochloride monohydrate | Initial report | 21.01.2026 | Production problem | NAROPIN 10mg/ml Amp.10ml Solution for injection | |
| Ropivacaine hydrochloride monohydrate | Initial report | 21.01.2026 | Other | NAROPIN 2 mg/ml Amp. 20 ml Solution for injection | |
| Quetiapine fumarate (Ph.Eur.) | Change notification | 21.01.2026 | Other | Seroquel Prolong 200 mg prolonged-release tablets | |
| Epirubicin hydrochloride | Change notification | 21.01.2026 | Production problem | Epirubicin Hikma 2 mg/ml concentrate for solution for infusion | |
| Vancomycin hydrochloride | Change notification | 21.01.2026 | Other | Vancomycin CP 500mg | |
| Lidocaine hydrochloride monohydrate | Change notification | 21.01.2026 | Other | Xylocaine Gel 2% | |
| Cyclophosphamide monohydrate | Initial report | 21.01.2026 | Production problem | Endoxan 200 mg | |
| Cyclophosphamide monohydrate | Initial report | 21.01.2026 | Production problem | Endoxan 500 mg | |
| Cyclophosphamide monohydrate | Initial report | 21.01.2026 | Production problem | Endoxan 1 g | |
| Ifosfamide | Initial report | 21.01.2026 | Production problem | Holoxan | |
| Phenobarbital sodium | Change notification | 20.01.2026 | Other | Luminal injection solution | |
| Salbutamol sulfate | Initial report | 20.01.2026 | Other | Bronchospray Autohaler | |
| Lorazepam | Change notification | 20.01.2026 | Other | Tavor 2.5 mg Expidet | |
| Epinephrine/Adrenaline | Change notification | 20.01.2026 | Production problem | Anapen 500 micrograms solution for injection | |
| Insulin glargine | Change notification | 20.01.2026 | Other | Semglee | |
| Insulin glargine | Change notification | 20.01.2026 | Other | Semglee 100 units/ml solution for injection in pre-filled pen – OP (5x3ml) | |
| Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) | Change notification | 20.01.2026 | Other | Ferrlecit 40 mg | |
| Iron(III) sodium D-gluconate hydroxide oxide complex (approx. 2:1:1:x:y) | Change notification | 20.01.2026 | Other | Ferrlecit 62.5 mg | |
| Tamsulosin hydrochloride | Change notification | 20.01.2026 | Other | Tamsulosin hydrochloride PUREN 0.4 mg prolonged-release capsules | |
| Pregabalin | Change notification | 20.01.2026 | Other | Pregabalin Aurobindo 25 mg hard capsules | |
| Buprenorphine hydrochloride | Change notification | 20.01.2026 | Other | Buprenorphine PUREN 8 mg sublingual tablets | |
| Atorvastatin calcium trihydrate (Ph.Eur.) | Change notification | 20.01.2026 | Other | Atorvastatin PUREN 40 mg film-coated tablets | |
| Rosuvastatin calcium (Ph.Eur.) | Change notification | 20.01.2026 | Other | Rosuvastatin Aurobindo 20 mg film-coated tablets | |
| Anastrozole | Change notification | 20.01.2026 | Other | Anastrozole Denk 1 mg film-coated tablets | |
| Propranolol hydrochloride | Initial report | 19.01.2026 | Other | DOCITON 10mg | |
| Nitrendipine | Initial report | 19.01.2026 | Other | Nitrendipine Aristo 10 mg film-coated tablets | |
| Arsenic(III) oxide | Change notification | 19.01.2026 | Other | TRISENOX 2 mg/ml concentrate for solution for infusion | |
| Dinoprost | Initial report | 19.01.2026 | Other | Propess 10 mg vaginal delivery system | |
| Adalimumab | Change notification | 19.01.2026 | Other | Amsparity | |
| Adalimumab | Change notification | 19.01.2026 | Other | Amsparity | |
| Methanthelinium bromide | Initial report | 19.01.2026 | Production problem | Vagantin RIEMSER | |
| Betamethasone dipropionate (Ph.Eur.); salicylic acid | Initial report | 19.01.2026 | Other | Soderm plus solution 0.64 mg/g + 20 mg/g solution for application to the skin |
| Active ingredients | Status | Update | Specialty |
| gozetotide | Stock shortage | 23/01/2026 | Locametz 25 micrograms, kit for radiopharmaceutical preparation |
| aprepitant | Supply tension | 23/01/2026 | Emend 125 mg, powder for oral suspension |
| spiramycin | Supply tension | 23/01/2026 | Rovamycin 1.5 million IU, lyophilisate for parenteral use |
| ketoprofen | Supply tension | 23/01/2026 | Ketoprofen Pharmy II 100 mg/2 mL, intramuscular (I.M.) injection solution |
| methylprednisolone (hydrogen succinate) | Supply tension | 23/01/2026 | Methylprednisolone Viatris 40 mg, powder for solution for injection (IM-IV) |
| methylprednisolone (hydrogen succinate) | Supply tension | 23/01/2026 | Methylprednisolone Viatris 120 mg, powder for solution for injection (IM-IV) |
| tropatépine (hydrochloride) | Supply tension | 22/01/2026 | Lepticur 10 mg, tablet |
| chlorpromazine (hydrochloride) | Return to availability | 22/01/2026 | Largactil 100 mg, film-coated tablet |
| chlorpromazine (hydrochloride) | Return to availability | 22/01/2026 | Largactil 25 mg, film-coated tablet |
| propranolol hydrochloride | Supply tension | 22/01/2026 | Propranolol 40 mg tablets |
| dipyridamole | Return to availability | 21/01/2026 | Persantine 10 mg/2 mL, injectable solution, ampoule |
| fluvoxamine (maleate) | Supply tension | 20/01/2026 | Fluvoxamine 100 mg, film-coated tablet |
| isoniazid, pyrazinamid, rifampicin | Supply tension | 19/01/2026 | Rifater, coated tablet |
| rifampicin | Supply tension | 19/01/2026 | Rifadine 300 mg, capsule, box of 30 |
| pregabalin | Supply tension | 19/01/2026 | Lyrica 20 mg/mL, oral solution |
| varenicline (tartrate) | Return to availability | 19/01/2026 | Champix 0.5 mg and 1 mg, film-coated tablet |
| Ingredients | Product Name | Formulation | Report Category | Report Date |
| Human Papillomavirus-16 L1 (Host: Trichoplusia ni Hi-5 Rix4446, Vector: rBaculo4449), Human Papillomavirus-18 L1 (Host: Trichoplusia ni Hi-5 Rix4446, Vector: rBaculo4450) | Suvarix Prefilled Syringe [Human Papillomavirus Vaccine (Recombinant)] | Suspension Injection | Discontinued | 2026-01-23 |
| Sodium Bicarbonate | Daewon Sodium Bicarbonate Injection (8.4%) | Solution for Injection | Supply Shortage | 2026-01-22 |
| Ketorolac Tromethamine | Acuveil Eye Drops 0.45% (Ketorolac Tromethamine Salt) (Single-Use) | Eye Drops | Supply Shortage | 2026-01-21 |
| Active ingredients | Dosage form | Quantity of active ingredients | Shortage status | Availability | Reason | Last updated |
| calcitonin salmon | Injection, solution | 100 IU/mL | Anticipated | Available | Unexpected increase in consumer demand | 23/01/2026 |
| lamotrigine | Tablet, chewable | 25 mg | Anticipated | Available | Manufacturing | 23/01/2026 |
| lamotrigine | Tablet, chewable | 200 mg | Anticipated | Available | Manufacturing | 23/01/2026 |
| cyproterone acetate | Tablet, uncoated | 50 mg | Resolved | Available | Manufacturing | 23/01/2026 |
| aripiprazole | Tablet, uncoated | 10 mg | Current | Limited Availability | Manufacturing | 23/01/2026 |
| mirtazapine | Tablet, film coated | 15 mg | Current | Limited Availability | Manufacturing | 23/01/2026 |
| quetiapine fumarate | Tablet, modified release | 172.695 mg | Anticipated | Available | Manufacturing | 23/01/2026 |
| elotuzumab | Injection, powder for | 340 mg | Anticipated | Available | Manufacturing | 23/01/2026 |
| trientine dihydrochloride | Capsule | 250 mg | Discontinued | Reduction in supply until supply is exhausted | Manufacturing | 23/01/2026 |
| lamotrigine | Tablet, chewable | 25 mg | Anticipated | Available | Manufacturing | 23/01/2026 |
| lamotrigine | Tablet, chewable | 200 mg | Current | Unavailable | Manufacturing | 23/01/2026 |
| rosuvastatin calcium | Tablet, film coated | 20.84 mg | Anticipated | Available | Manufacturing | 23/01/2026 |
| tirzepatide | Injection, solution | 5 mg | Discontinued | Unavailable | Commercial Changes / Commercial viability | 23/01/2026 |
| tirzepatide | Injection, solution | 7.5 mg | Discontinued | Unavailable | Commercial Changes / Commercial viability | 23/01/2026 |
| tirzepatide | Injection, solution | 12.5 mg | Discontinued | Unavailable | Commercial Changes / Commercial viability | 23/01/2026 |
| tirzepatide | Injection, solution | 10 mg | Discontinued | Unavailable | Commercial Changes / Commercial viability | 23/01/2026 |
| tirzepatide | Injection, solution | 15 mg | Discontinued | Unavailable | Commercial Changes / Commercial viability | 23/01/2026 |
| tirzepatide | Injection, solution | 2.5 mg | Discontinued | Unavailable | Commercial Changes / Commercial viability | 23/01/2026 |
| clindamycin phosphate | Cream | 22.8 mg/g | Anticipated | Available | Unexpected increase in consumer demand | 23/01/2026 |
| gliclazide | Tablet, uncoated | 80 mg | Anticipated | Available | Manufacturing | 23/01/2026 |
| methylphenidate hydrochloride | Capsule, modified release | 20 mg | Resolved | Available | Manufacturing | 23/01/2026 |
| digoxin | Injection, solution | .25 mg/mL | Resolved | Available | Manufacturing | 22/01/2026 |
| codeine phosphate hemihydrate | Oral Liquid, solution | 5 mg/mL | Current | Unavailable | Manufacturing | 22/01/2026 |
| lidocaine | Spray, solution | 100 mg/mL | Anticipated | Available | Manufacturing | 22/01/2026 |
| ciprofloxacin hydrochloride | Tablet, film coated | 832.5 mg | Current | Unavailable | Manufacturing | 22/01/2026 |
| olanzapine pamoate monohydrate | Injection, powder for | 690 mg | Resolved | Available | Transport / Logistic issues / Storage capacity issues | 22/01/2026 |
| nortriptyline | Tablet, film coated | 10 mg | Current | Limited Availability | Manufacturing | 22/01/2026 |
| aripiprazole | Tablet, uncoated | 10 mg | Resolved | Available | Manufacturing | 22/01/2026 |
| galantamine hydrobromide | Capsule, modified release | 20.512 mg | Resolved | Available | Unexpected increase in demand due to other sponsors unable to supply | 22/01/2026 |
| pramipexole dihydrochloride monohydrate | Tablet | 1 mg | Resolved | Available | Manufacturing | 22/01/2026 |
| ondansetron hydrochloride dihydrate | Tablet, film coated | 9.972 mg | Resolved | Available | Manufacturing | 22/01/2026 |
| metronidazole | Tablet, uncoated | 400 mg | Current | Unavailable | Manufacturing | 22/01/2026 |
| mirtazapine | Tablet, orally disintegrating | 15 mg | Anticipated | Available | Manufacturing | 22/01/2026 |
| montelukast sodium | Tablet, chewable | 4.16 mg | Resolved | Available | Manufacturing | 22/01/2026 |
| montelukast sodium | Tablet | 10.4 mg | Anticipated | Available | Commercial Changes / Commercial viability | 22/01/2026 |
| quetiapine fumarate | Tablet, modified release | 172.695 mg | Current | Limited Availability | Manufacturing | 22/01/2026 |
| candesartan cilexetil~hydrochlorothiazide | Tablet, uncoated | 16 mg~12.5 mg | Anticipated | Available | Manufacturing | 22/01/2026 |
| ezetimibe | Tablet, uncoated | 10 mg | Current | Unavailable | Unexpected increase in consumer demand | 22/01/2026 |
| codeine phosphate hemihydrate | Oral Liquid | 5 mg/mL | Anticipated | Available | Unexpected increase in demand due to other sponsors unable to supply | 22/01/2026 |
| hydrochlorothiazide~olmesartan medoxomil | Tablet | 12.5 mg~40 mg | Current | Unavailable | Manufacturing | 22/01/2026 |
| ondansetron hydrochloride dihydrate | Tablet, film coated | 9.972 mg | Resolved | Available | Manufacturing | 22/01/2026 |
| amlodipine besilate~olmesartan medoxomil | Tablet, film coated | 6.935 mg~20 mg | Current | Limited Availability | Manufacturing | 22/01/2026 |
| amlodipine besilate~olmesartan medoxomil | Tablet, film coated | 6.935 mg~40 mg | Current | Limited Availability | Manufacturing | 22/01/2026 |
| lacosamide | Tablet, film coated | 50 mg | Anticipated | Available | Manufacturing | 22/01/2026 |
| doxepin hydrochloride | Capsule, hard | 11.3 mg | Current | Unavailable | Manufacturing | 22/01/2026 |
| aprepitant | Capsule, hard | 165 mg | Anticipated | Available | Manufacturing | 22/01/2026 |
| gliclazide | Tablet, uncoated | 80 mg | Anticipated | Available | Manufacturing | 22/01/2026 |
| nitrofurantoin | Capsule, hard | 50 mg | Anticipated | Available | Unexpected increase in consumer demand | 22/01/2026 |
| nitrofurantoin | Capsule, hard | 100 mg | Current | Limited Availability | Unexpected increase in consumer demand | 22/01/2026 |
| nitrofurantoin | Capsule, hard | 100 mg | Current | Unavailable | Unexpected increase in consumer demand | 22/01/2026 |
| atracurium besilate | Injection, solution | 10 mg/mL | Resolved | Available | Manufacturing | 22/01/2026 |
| olanzapine | Tablet, film coated | 5 mg | Resolved | Available | Transport / Logistic issues / Storage capacity issues | 22/01/2026 |
| doxepin hydrochloride | Capsule, hard | 28.25 mg | Current | Unavailable | Manufacturing | 22/01/2026 |
| naratriptan hydrochloride | Tablet, film coated | 2.78 mg | Current | Unavailable | Manufacturing | 22/01/2026 |
| ziprasidone hydrochloride monohydrate | Capsule, hard | 22.65 mg | Anticipated | Available | Manufacturing | 22/01/2026 |
| desferrioxamine mesilate | Injection, powder for | 2 g | Current | Limited Availability | Manufacturing | 22/01/2026 |
| ciprofloxacin hydrochloride | Tablet, film coated | 873.32 mg | Resolved | Available | Manufacturing | 22/01/2026 |
| ciprofloxacin hydrochloride | Tablet, film coated | 582.21 mg | Current | Limited Availability | Manufacturing | 22/01/2026 |
| parecoxib sodium | Injection, powder for | 42.36 mg | Anticipated | Available | Manufacturing | 22/01/2026 |
| lamotrigine | Tablet, dispersible | 200 mg | Current | Unavailable | Manufacturing | 22/01/2026 |
| Coxiella burnetii | Injection | 50 microgram/mL | Current | Limited Availability | Manufacturing | 21/01/2026 |
| lidocaine hydrochloride | Gel | 20 mg/g | Anticipated | Available | Manufacturing | 21/01/2026 |
| ibuprofen~codeine phosphate hemihydrate | Tablet, film coated | 200 mg~12.8 mg | Discontinued | Reduction in supply until supply is exhausted | Commercial Changes / Commercial viability | 21/01/2026 |
| Somatropin | Injection, powder for | 5 mg/mL | Anticipated | Available | Unexpected increase in consumer demand | 21/01/2026 |
| phenylephrine hydrochloride~prednisolone acetate | Eye Drops, suspension | 1.2 mg/mL~10 mg/mL | Current | Limited Availability | Unexpected increase in consumer demand | 21/01/2026 |
| aprepitant | Capsule | 165 mg | Anticipated | Available | Manufacturing | 21/01/2026 |
| oseltamivir phosphate | Capsule, hard | 98.5 mg | Current | Unavailable | Unexpected increase in consumer demand | 21/01/2026 |
| sacubitril~valsartan | Tablet, film coated | 48.6 mg~51.4 mg | Current | Unavailable | Manufacturing | 21/01/2026 |
| valsartan~sacubitril | Tablet, film coated | 25.7 mg~24.3 mg | Current | Unavailable | Manufacturing | 21/01/2026 |
| valsartan~sacubitril | Tablet, film coated | 102.8 mg~97.2 mg | Current | Unavailable | Manufacturing | 21/01/2026 |
| flunitrazepam | Tablet, film coated | 1 mg | Current | Unavailable | Manufacturing | 21/01/2026 |
| galantamine hydrobromide~galantamine | Capsule, modified release | 10.25 mg~8 mg | Current | Limited Availability | Unexpected increase in demand due to other sponsors unable to supply | 21/01/2026 |
| galantamine~galantamine hydrobromide | Capsule, modified release | 24 mg~30.76 mg | Current | Limited Availability | Unexpected increase in demand due to other sponsors unable to supply | 21/01/2026 |
| lamotrigine | Tablet, chewable | 50 mg | Resolved | Available | Manufacturing | 20/01/2026 |
| tranexamic acid | Injection, solution | 1000 mg | Discontinued | Unavailable | Manufacturing | 20/01/2026 |
| riluzole | Tablet, film coated | 50 mg | Current | Unavailable | Manufacturing | 20/01/2026 |
| atorvastatin calcium trihydrate | Tablet, film coated | 21.69 mg | Current | Unavailable | Manufacturing | 20/01/2026 |
| pramipexole dihydrochloride monohydrate | Tablet | .25 mg | Current | Unavailable | Unexpected increase in consumer demand | 20/01/2026 |
| metformin hydrochloride | Tablet, modified release | 1000 mg | Resolved | Available | Manufacturing | 20/01/2026 |
| rosuvastatin calcium | Tablet, film coated | 10.42 mg | Current | Unavailable | Manufacturing | 20/01/2026 |
| bimatoprost | Eye Drops | .3 mg/mL | Current | Unavailable | Manufacturing | 20/01/2026 |
| methylphenidate hydrochloride | Capsule, modified release | 60 mg | Current | Limited Availability | Manufacturing | 20/01/2026 |
| tadalafil | Tablet | 10 mg | Discontinued | Reduction in supply until supply is exhausted | Manufacturing | 20/01/2026 |
| temozolomide | Capsule, hard | 5 mg | Anticipated | Available | Manufacturing | 20/01/2026 |
| methylphenidate hydrochloride | Capsule, modified release | 40 mg | Current | Limited Availability | Manufacturing | 20/01/2026 |
| rifampicin | Oral Liquid | 20 mg/mL | Anticipated | Available | Unexpected increase in consumer demand | 19/01/2026 |
| lidocaine hydrochloride | Injection, concentrated | 100 mg/mL | Anticipated | Available | Manufacturing | 19/01/2026 |
| topiramate | Tablet, film coated | 25 mg | Resolved | Available | Manufacturing | 19/01/2026 |
| risperidone | Tablet | 1 mg | Resolved | Available | Unexpected increase in demand due to other sponsors unable to supply | 19/01/2026 |
| calcium folinate hydrate | Tablet, uncoated | 18.6 mg | Resolved | Available | Unexpected increase in consumer demand | 19/01/2026 |
| levetiracetam | Tablet, film coated | 500 mg | Resolved | Available | Manufacturing | 19/01/2026 |
| pramipexole dihydrochloride monohydrate | Tablet | .125 mg | Current | Unavailable | Manufacturing | 19/01/2026 |
| sildenafil citrate | Tablet, film coated | 140.45 mg | Resolved | Available | Unexpected increase in demand due to other sponsors unable to supply | 19/01/2026 |
| ondansetron hydrochloride dihydrate | Tablet, film coated | 4.986 mg | Resolved | Available | Manufacturing | 19/01/2026 |
| indapamide hemihydrate | Tablet, sugar coated | 2.5 mg | Current | Unavailable | Manufacturing | 19/01/2026 |
| montelukast sodium | Tablet, chewable | 4.16 mg | Current | Unavailable | Manufacturing | 19/01/2026 |
| ambrisentan | Tablet, film coated | 10 mg | Resolved | Available | Manufacturing | 19/01/2026 |
| moxonidine | Tablet, film coated | 400 microgram | Current | Limited Availability | Commercial Changes / Commercial viability | 19/01/2026 |
| moxonidine | Tablet, film coated | 200 microgram | Current | Unavailable | Commercial Changes / Commercial viability | 19/01/2026 |
| rasagiline mesilate | Tablet | 1.56 mg | Current | Unavailable | Manufacturing | 19/01/2026 |
| eplerenone | Tablet, film coated | 50 mg | Resolved | Available | Manufacturing | 19/01/2026 |
| eplerenone | Tablet, film coated | 25 mg | Resolved | Available | Manufacturing | 19/01/2026 |
| levothyroxine sodium | Tablet | .075 mg | Current | Limited Availability | Manufacturing | 19/01/2026 |
January 20, 2026
January 23, 2026
January 22, 2026
January 21, 2026
January 20, 2026
January 19, 2026

