海外医薬品不足情報｜医薬政策企画 P-Cubed

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2025.08.18 [ ドイツ ]

BfArMボトルネック・レポート（2025年8月11日～8月17日）

Active ingredients

Report type

Date of last message

Type of reason

AM designation

Sertraline hydrochloride

Change notification

15.08.2025

Other

Sertraline TAD 100 mg film-coated tablets

Sertraline hydrochloride

Change notification

15.08.2025

Other

Sertraline TAD 50 mg film-coated tablets

Phenoxybenzamine hydrochloride

Change notification

15.08.2025

Other

Dibenzyran 10

Atorvastatin calcium trihydrate (Ph.Eur.)

Change notification

15.08.2025

Other

Atorvastatin Micro Labs 20 mg film-coated tablets

Atorvastatin calcium trihydrate (Ph.Eur.)

Change notification

15.08.2025

Other

Atorvastatin Micro Labs 40 mg film-coated tablets

Atorvastatin calcium trihydrate (Ph.Eur.)

Change notification

15.08.2025

Other

Atorvastatin Micro Labs 80 mg film-coated tablets

Rifampicin

Change notification

15.08.2025

Production problem

EREMFAT 450 mg

Acetylcholine chloride

Change notification

15.08.2025

Production problem

Miochol-E powder and solvent for the preparation of an instillation solution for intraocular use

Azithromycin dihydrate

Change notification

15.08.2025

Other

Azithromycin AL 250 mg film-coated tablets

Galantamine hydrobromide

Change notification

14.08.2025

Production problem

Galantamine Heumann 24 mg hard capsules, delayed release

Quetiapine fumarate (Ph.Eur.)

Change notification

14.08.2025

Production problem

Quetiapine Heumann retard 200 mg prolonged-release tablets

Quetiapine fumarate (Ph.Eur.)

Change notification

14.08.2025

Production problem

Quetiapine Heumann retard 150 mg prolonged-release tablets

Quetiapine fumarate (Ph.Eur.)

Change notification

14.08.2025

Production problem

Quetiapine Heumann retard 50 mg prolonged-release tablets

Sodium diphosphate decahydrate for the manufacture of radioactive medicinal products

Initial

14.08.2025

Other

Technescan PYP

Tobramycin

Change notification

14.08.2025

Production problem

TOBI Podhaler 28 mg hard capsules with powder for inhalation – OP224(4×56)

Alprazolam

Initial

14.08.2025

Other

Alprazolam-ratiopharm 1.0 mg tablets

Emtricitabine; tenofovir disoproxil maleate

Change notification

14.08.2025

Other

Emtricitabine/tenofovir disoproxil Mylan 200 mg/245 mg film-coated tablets – OP30(Fl)

Naloxegol oxalate

Initial

13.08.2025

Other

Moventig 25 mg film-coated tablets – OP100(100×1)

Isoniazid

Change notification

13.08.2025

Other

Isozid 200 mg

Methyl (5-amino-4-oxopentanoate) hydrochloride

Change notification

12.08.2025

Other

Metvix 160 mg/g cream

Olanzapine

Initial

12.08.2025

Production problem

Olanzapine Glenmark 5 mg tablets – OP70

Olanzapine

Initial

12.08.2025

Production problem

Olanzapine Glenmark 2.5 mg tablets – OP70

Olanzapine

Initial

12.08.2025

Production problem

Olanzapine Glenmark 2.5 mg tablets – OP56

Olanzapine

Initial

12.08.2025

Production problem

Olanzapine Glenmark 10 mg tablets – OP70

Olanzapine

Initial

12.08.2025

Production problem

Olanzapine Glenmark 10 mg tablets – OP56

Trazodone hydrochloride

Change notification

12.08.2025

Production problem

Trazodone Glenmark 100 mg tablets

Rizatriptan benzoate

Change notification

12.08.2025

Production problem

Rizatriptan Glenmark 10 mg tablets

Rizatriptan benzoate

Change notification

12.08.2025

Production problem

Rizatriptan Glenmark 10 mg orodispersible tablets

Rizatriptan benzoate

Change notification

12.08.2025

Production problem

Rizatriptan Glenmark 5 mg orodispersible tablets

Rizatriptan benzoate

Change notification

12.08.2025

Production problem

Rizatriptan Glenmark 5 mg tablets

Quetiapine fumarate (Ph.Eur.)

Initial

12.08.2025

Production problem

Quetiapine Glenmark 300 mg prolonged-release tablets

Quetiapine fumarate (Ph.Eur.)

Change notification

12.08.2025

Production problem

Quetiapine Glenmark 400 mg prolonged-release tablets

Quetiapine fumarate (Ph.Eur.)

Change notification

12.08.2025

Production problem

Quetiapine Glenmark 200 mg prolonged-release tablets

Quetiapine fumarate (Ph.Eur.)

Change notification

12.08.2025

Production problem

Quetiapine Glenmark 150 mg prolonged-release tablets

Mometasone furoate (Ph.Eur.)

Change notification

12.08.2025

Production problem

Mometasone Glenmark 1 mg/g ointment

Linezolid

Change notification

12.08.2025

Production problem

Linezolid Glenmark 600 mg film-coated tablets

Galantamine hydrobromide

Change notification

12.08.2025

Production problem

Galantamine Glenmark 24 mg hard capsules, delayed release

Galantamine hydrobromide

Change notification

12.08.2025

Production problem

Galantamine Glenmark 8 mg hard capsules, delayed release

Galantamine hydrobromide

Change notification

12.08.2025

Production problem

Galantamine Glenmark 16 mg hard capsules, delayed release

Pirfenidone

Initial

12.08.2025

Production problem

Pirfenidone Accord 801 mg film-coated tablets

Ezetimibe; Simvastatin

Initial

12.08.2025

Production problem

Ezetimibe/Simvastatin Glenmark 10 mg/20 mg tablets

Alprazolam

Initial

12.08.2025

Other

Alprazolam – 1 A Pharma 1 mg tablets

Alprazolam

Initial

12.08.2025

Other

Alprazolam – 1 A Pharma 0.5 mg tablets

Gabapentin

Initial

12.08.2025

Production problem

Gabapentin Holsten 800 mg film-coated tablets

Gabapentin

Initial

12.08.2025

Other

Gabapentin Holsten 100 mg hard capsules

Doxepine hydrochloride (Ph.Eur.)

Initial

12.08.2025

Other

Doxepin 75 Holsten

Zoledronic acid monohydrate

Change notification

12.08.2025

Production problem

Zoledronic acid Mylan 4 mg/5 ml concentrate for solution for infusion – OP5ml

Rifampicin

Initial

12.08.2025

Other

EREMFAT 300 mg

Vancomycin hydrochloride

Initial

12.08.2025

Other

Vancomycin “Lederle” 1000 mg

Urapidil

Change notification

12.08.2025

Other

Urapidil PUREN 90 mg prolonged-release capsules

Topiramate

Change notification

12.08.2025

Production problem

Topiramate PUREN 100 mg film-coated tablets

Sitagliptin hydrochloride monohydrate

Change notification

12.08.2025

Production problem

Sitagliptin PUREN 50 mg film-coated tablets

Sitagliptin hydrochloride monohydrate

Change notification

12.08.2025

Production problem

Sitagliptin Aurobindo 25 mg film-coated tablets

Rizatriptan benzoate

Change notification

12.08.2025

Production problem

Rizatriptan PUREN 5 mg tablets

Rizatriptan benzoate

Change notification

12.08.2025

Other

Rizatriptan PUREN 10 mg tablets

Rizatriptan benzoate

Change notification

12.08.2025

Other

Rizatriptan Aurobindo 10 mg orodispersible tablets

Risperidone

Change notification

12.08.2025

Other

Risperidone PUREN 1 mg film-coated tablets

Risperidone

Change notification

12.08.2025

Other

Risperidone Aurobindo 1 mg film-coated tablets

Docetaxel

Change notification

12.08.2025

Other

Docetaxel Aurobindo 20 mg/ml concentrate for solution for infusion

Nevirapine

Change notification

12.08.2025

Other

Nevirapine Aurobindo 400 mg prolonged-release tablets

Moxifloxacin hydrochloride (Ph.Eur.) (with information on water content (1:x))

Change notification

12.08.2025

Production problem

Moxifloxacin Aurobindo 400 mg film-coated tablets

Moxifloxacin hydrochloride (Ph.Eur.) (with information on water content (1:x))

Change notification

12.08.2025

Production problem

Moxifloxacin PUREN 400 mg film-coated tablets

Ibuprofen

Change notification

12.08.2025

Other

IBU-PUREN acute 400 mg film-coated tablets

Oxycodone hydrochloride (Ph.Eur.)

Change notification

11.08.2025

Other

Oxygesic 5 mg

Paliperidone palmitate

Change notification

11.08.2025

Production problem

Paliperidone Advanz Pharma 25 mg Depot injection suspension in a pre-filled syringe

Paliperidone palmitate

Change notification

11.08.2025

Production problem

Paliperidone Advanz Pharma 50 mg depot injection suspension in a pre-filled syringe

Hydromorphone hydrochloride

Change notification

11.08.2025

Other

Hydromorphone HEXAL 2.6 mg hard capsules

Insulin aspart

Initial

11.08.2025

Other

NovoRapid PumpCart 100 E/ml injection solution in cartridge – OP[5x(5×1.6ml)]

Chlortalidone

Change notification

11.08.2025

Other

Chlortalidone HEXAL 25 mg tablets

Chlortalidone

Change notification

11.08.2025

Other

Chlortalidone HEXAL 50 mg tablets

Sufentanil

Initial

11.08.2025

Production problem

Sufentanil-hameln 50 micrograms/ml injection/infusion solution

Oxycodone hydrochloride (Ph.Eur.)

Initial

11.08.2025

Other

Oxycodone-HCl HEXAL 40 mg prolonged-release tablets

Oxycodone hydrochloride (Ph.Eur.)

Initial

11.08.2025

Other

Oxycodone-HCl HEXAL 20 mg prolonged-release tablets

Oxycodone hydrochloride (Ph.Eur.)

Initial

11.08.2025

Other

Oxycodone-HCl HEXAL 10 mg prolonged-release tablets

Oxycodone hydrochloride (Ph.Eur.)

Initial

11.08.2025

Other

Oxycodone-HCl HEXAL 5 mg prolonged-release tablets

Hydromorphone hydrochloride

Change notification

11.08.2025

Other

Hydromorphone HCl PUREN 4 mg hard capsules, delayed release

Escitalopram oxalate

Change notification

11.08.2025

Other

Escitalopram Aurobindo 10 mg film-coated tablets

Etoricoxib

Change notification

11.08.2025

Other

Etoricoxib PUREN 120 mg film-coated tablets

Atorvastatin calcium trihydrate (Ph.Eur.)

Change notification

11.08.2025

Other

Atorvastatin PUREN 40 mg film-coated tablets

Gabapentin

Change notification

11.08.2025

Other

Gabapentin Aurobindo 400 mg hard capsules

Prasugrel

Change notification

11.08.2025

Production problem

Prasugrel PUREN 5 mg film-coated tablets

Lamotrigine

Change notification

11.08.2025

Production problem

Lamotrigine Aurobindo 50 mg tablets

Ramipril

Change notification

11.08.2025

Other

Ramipril PUREN 5 mg tablets

Pregabalin

Change notification

11.08.2025

Other

Pregabalin Aurobindo 25 mg hard capsules

Pregabalin

Change notification

11.08.2025

Other

Pregabalin PUREN 100 mg hard capsules

2025.08.18 [ フランス ]

ANSMフランス供給不足情報（2025年8月11日～8月17日）

Active ingredients	Statut	Update	Specialty
bumetanide	Supply tension	14/08/2025	Burinex 2 mg/4 ml IV, solution for injection in ampoule
alglucosidase alfa ((mammalian/hamster/cho cells))	Supply tension	14/08/2025	Myozyme 50 mg, powder for solution for diluted infusion
basiliximab (mammal/mouse/Sp2/O)	Available for use	14/08/2025	Simulect 20 mg, powder and solvent for solution for injection or infusion
glucagon (hydrochloride)	Supply tension	14/08/2025	GlucaGen Kit 1 mg/ml, powder and solvent for solution for injection
bezafibrate	Supply tension	13/08/2025	Befizal L.P. 400 mg, sustainedrelease coated tablet
methylphenidate hydrochloride	Supply tension	13/08/2025	Concerta LP, extendedrelease tablet
methylprednisolone (hydrogen succinate)	Supply tension	13/08/2025	Methylprednisolone Viatris 40 mg, powder for solution for injection (IMIV)
methylprednisolone (hydrogen succinate)	Out of stock	13/08/2025	Methylprednisolone Viatris 20 mg, powder for solution for injection (IMIV)
naloxegol (oxalate)	Available for use	13/08/2025	Moventig 25 mg, filmcoated tablet
naloxegol (oxalate)	Available for use	13/08/2025	Moventig 12.5 mg, filmcoated tablet
betamethasone (dipropionate), betamethasone (sodium phosphate)	Supply tension	12/08/2025	Diprostene, suspension for injection in prefilled syringe
chlorpromazine (hydrochloride)	Supply tension	12/08/2025	Largactil 100 mg, scored filmcoated tablet
medroxyprogesterone	Supply tension	11/08/2025	Depo Prodasone 500 mg, injectable suspension –
bromfenac sodium sesquihydrate	Supply tension	11/08/2025	Yellox 0.9 mg/ml, eye drops solution
methotrexate	Available for use	11/08/2025	Methotrexate Teva 10 per cent (5 g/50 mL), solution for injection
levofloxacin	Available for use	11/08/2025	Specialties based on Levofloxacin 500 mg scored filmcoated tablet
temozolomide	Supply tension	11/08/2025	Temodal 2.5 mg/ml, powder for solution for infusion
bosentan monohydrate	Available for use	11/08/2025	Bosentan Viatris 125 mg, filmcoated tablet

2025.08.18 [ オーストラリア ]

TGAオーストラリア供給不足情報（2025年8月11日～8月17日）

Active ingredients	Dosage form	Quantity of active ingredients	Shortage status	Availability	Reason	Last updated
naproxen	Tablet, modified release	750 mg	Anticipated	Available	Manufacturing	15/08/2025
Measles virus~Rubella virus~live varicella vaccine~Mumps virus	Injection, powder for	1000 CCID50~1000 CCID50~1995 PFU~25119 CCID50	Current	Limited Availability	Manufacturing	15/08/2025
propofol	Injection, emulsion	1000 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	15/08/2025
aripiprazole	Tablet, uncoated	30 mg	Current	Limited Availability	Manufacturing	15/08/2025
bisoprolol fumarate	Tablet	2.5 mg	Anticipated	Available	Manufacturing	15/08/2025
bisoprolol fumarate	Tablet	5 mg	Anticipated	Available	Manufacturing	15/08/2025
bisoprolol fumarate	Tablet	10 mg	Anticipated	Available	Manufacturing	15/08/2025
ondansetron hydrochloride dihydrate	Tablet, film coated	9.972 mg	Current	Limited Availability	Manufacturing	15/08/2025
indapamide hemihydrate	Tablet, sugar coated	2.5 mg	Anticipated	Available	Manufacturing	15/08/2025
milrinone	Injection, concentrated	10 mg	Current	Limited Availability	Manufacturing	15/08/2025
clopidogrel besilate	Tablet, film coated	112.1 mg	Current	Unavailable	Manufacturing	15/08/2025
Pneumococcal purified capsular polysaccharides	Injection, solution	50 microgram/mL	Resolved	Available	Unexpected increase in consumer demand	15/08/2025
pramipexole dihydrochloride monohydrate	Tablet	.125 mg	Current	Limited Availability	Unexpected increase in consumer demand	15/08/2025
pramipexole dihydrochloride monohydrate	Tablet	.25 mg	Current	Unavailable	Unexpected increase in consumer demand	15/08/2025
live varicella vaccine	Injection, powder for	4000 PFU/mL	Resolved	Available	Unexpected increase in demand due to other sponsors unable to supply	15/08/2025
nizatidine	Capsule, hard	150 mg	Current	Unavailable	Manufacturing	15/08/2025
sildenafil citrate	Tablet, film coated	140.48 mg	Current	Limited Availability	Manufacturing	15/08/2025
sildenafil citrate	Tablet, film coated	70.24 mg	Current	Unavailable	Unexpected increase in consumer demand	15/08/2025
sildenafil citrate	Tablet, film coated	140.48 mg	Current	Limited Availability	Manufacturing	15/08/2025
melatonin	Capsule, hard	2 mg	Resolved	Available	Unexpected increase in consumer demand	15/08/2025
reboxetine mesilate	Tablet, uncoated	5.224 mg	Resolved	Available	Manufacturing	15/08/2025
propofol	Injection, emulsion	500 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	14/08/2025
risperidone	Tablet, film coated	1 mg	Anticipated	Available	Manufacturing	14/08/2025
propofol	Injection, emulsion	500 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	14/08/2025
mycophenolate mofetil	Capsule	250 mg	Current	Unavailable	Manufacturing	14/08/2025
pramipexole dihydrochloride monohydrate	Tablet	.25 mg	Current	Unavailable	Manufacturing	14/08/2025
atorvastatin calcium trihydrate	Tablet, film coated	86.76 mg	Current	Unavailable	Manufacturing	14/08/2025
montelukast sodium	Tablet, chewable	4.16 mg	Current	Unavailable	Manufacturing	14/08/2025
ondansetron	Tablet, orally disintegrating	8 mg	Resolved	Available	Manufacturing	14/08/2025
atorvastatin calcium trihydrate~amlodipine besilate	Tablet, film coated	43.376 mg~13.88 mg	Anticipated	Available	Manufacturing	14/08/2025
docetaxel	Injection, concentrated	80 mg	Anticipated	Available	Manufacturing	14/08/2025
carboplatin	Injection, solution	450 mg	Anticipated	Available	Manufacturing	14/08/2025
citalopram hydrobromide	Tablet, film coated	49.98 mg	Current	Limited Availability	Manufacturing	14/08/2025
bimatoprost	Eye Drops	.3 mg/mL	Current	Unavailable	Manufacturing	14/08/2025
linezolid	Tablet, film coated	600 mg	Current	Unavailable	Manufacturing	14/08/2025
ezetimibe	Tablet, uncoated	10 mg	Current	Limited Availability	Unexpected increase in consumer demand	14/08/2025
azacitidine	Injection, powder for	100 mg	Current	Unavailable	Manufacturing	14/08/2025
irbesartan	Tablet, film coated	75 mg	Anticipated	Available	Manufacturing	14/08/2025
tadalafil	Tablet, film coated	10 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	14/08/2025
nizatidine	Capsule, hard	150 mg	Current	Unavailable	Manufacturing	14/08/2025
ivabradine hydrochloride	Tablet, film coated	5.39 mg	Current	Unavailable	Manufacturing	14/08/2025
mebeverine hydrochloride	Tablet, film coated	135 mg	Current	Limited Availability	Manufacturing	14/08/2025
metformin hydrochloride	Tablet, film coated	1000 mg	Resolved	Available	Manufacturing	14/08/2025
paclitaxel	Injection, powder for	100 mg	Current	Unavailable	Manufacturing	14/08/2025
pomalidomide	Capsule, hard	2 mg	Resolved	Available	Manufacturing	14/08/2025
avatrombopag maleate	Tablet, film coated	23.6 mg	Resolved	Available	Manufacturing	14/08/2025
levothyroxine sodium	Tablet	100 microgram	Current	Unavailable	Unexpected increase in consumer demand	14/08/2025
metformin hydrochloride~sitagliptin hydrochloride monohydrate	Tablet, film coated	500 mg~56.69 mg	Current	Unavailable	Manufacturing	14/08/2025
sitagliptin hydrochloride monohydrate~metformin hydrochloride	Tablet, film coated	56.69 mg~850 mg	Current	Unavailable	Manufacturing	14/08/2025
sirolimus	Oral Liquid, solution	1 mg/mL	Resolved	Available	Manufacturing	14/08/2025
ciprofloxacin hydrochloride	Tablet, film coated	873.32 mg	Anticipated	Available	Manufacturing	14/08/2025
Somatropin	Injection, powder for	12 mg/mL	Anticipated	Available	Unexpected increase in consumer demand	13/08/2025
acetylcysteine	Injection, concentrated	2 g	Current	Unavailable	Unexpected increase in demand due to other sponsors unable to supply	13/08/2025
bosentan monohydrate	Tablet, film coated	129.082 mg	Resolved	Available	Manufacturing	13/08/2025
tobramycin	Eye Ointment	3 mg/g	Resolved	Available	Manufacturing	13/08/2025
atorvastatin calcium trihydrate	Tablet, film coated	43.38 mg	Resolved	Available	Manufacturing	13/08/2025
levodopa~carbidopa monohydrate	Tablet, uncoated	100 mg~27 mg	Anticipated	Available	Manufacturing	13/08/2025
flucloxacillin sodium monohydrate	Injection, powder for	544.1 mg	Current	Limited Availability	Transport / Logistic issues / Storage capacity issues	13/08/2025
lanreotide acetate	Injection, solution	133.33 mg	Resolved	Available	Manufacturing	13/08/2025
cefalexin monohydrate	Capsule, hard	275 mg	Resolved	Available	Manufacturing	13/08/2025
propofol	Injection, emulsion	10 mg/mL	Resolved	Available	Manufacturing	13/08/2025
terbinafine hydrochloride	Tablet, uncoated	281.25 mg	Anticipated	Available	Manufacturing	12/08/2025
prazosin hydrochloride	Tablet, uncoated	1.095 mg	Resolved	Available	Unexpected increase in demand due to other sponsors unable to supply	12/08/2025
prazosin hydrochloride	Tablet, uncoated	5.476 mg	Anticipated	Available	Unexpected increase in consumer demand	12/08/2025
acetylcholine chloride	Solution, powder for irrigation	10 mg/mL	Current	Unavailable	Manufacturing	12/08/2025
tetrabenazine	Tablet, uncoated	25 mg	Anticipated	Available	Manufacturing	12/08/2025
ondansetron hydrochloride dihydrate	Injection, solution	5 mg	Current	Limited Availability	Manufacturing	12/08/2025
propranolol hydrochloride	Tablet, film coated	40 mg	Current	Unavailable	Manufacturing	12/08/2025
trimethoprim~sulfamethoxazole	Tablet, uncoated	160 mg~800 mg	Current	Limited Availability	Manufacturing	12/08/2025
ezetimibe~atorvastatin calcium trihydrate	Tablet, multilayer	10 mg~10.9 mg	Anticipated	Available	Manufacturing	12/08/2025
Infliximab	Injection, powder for	100 mg	Discontinued	Reduction in supply until supply is exhausted	Commercial Changes / Commercial viability	12/08/2025
methylphenidate hydrochloride	Capsule, modified release	60 mg	Current	Unavailable	Manufacturing	12/08/2025
solifenacin succinate	Tablet, film coated	5 mg	Current	Unavailable	Manufacturing	12/08/2025
ezetimibe~simvastatin	Tablet	10 mg~40 mg	Anticipated	Available	Unexpected increase in demand due to other sponsors unable to supply	12/08/2025
spironolactone	Tablet, uncoated	100 mg	Current	Limited Availability	Manufacturing	12/08/2025
Teriparatide	Injection, solution	.25 mg/mL	Current	Limited Availability	Unexpected increase in demand due to other sponsors unable to supply	12/08/2025
levothyroxine sodium	Tablet	75 microgram	Current	Unavailable	Manufacturing	12/08/2025
lorazepam	Tablet	1 mg	Current	Limited Availability	Manufacturing	12/08/2025
Teriparatide	Injection, solution	250 microgram/mL	Current	Limited Availability	Manufacturing	12/08/2025
albendazole	Tablet, chewable	400 mg	Resolved	Available	Manufacturing	12/08/2025
fampridine	Tablet, modified release	10 mg	Anticipated	Available	Transport / Logistic issues / Storage capacity issues	11/08/2025
pramipexole dihydrochloride monohydrate	Tablet	.125 mg	Current	Unavailable	Manufacturing	11/08/2025
ciprofloxacin hydrochloride	Tablet, film coated	277.5 mg	Current	Unavailable	Manufacturing	11/08/2025
ciprofloxacin hydrochloride	Tablet, film coated	555 mg	Current	Unavailable	Manufacturing	11/08/2025
ciprofloxacin hydrochloride	Tablet, film coated	832.5 mg	Current	Unavailable	Manufacturing	11/08/2025
metoprolol succinate	Tablet, modified release	95 mg	Current	Unavailable	Manufacturing	11/08/2025
metoprolol succinate	Tablet, modified release	47.5 mg	Current	Unavailable	Manufacturing	11/08/2025
metoprolol succinate	Tablet, modified release	190 mg	Current	Unavailable	Manufacturing	11/08/2025
metoprolol succinate	Tablet, modified release	23.75 mg	Current	Unavailable	Manufacturing	11/08/2025
entecavir	Tablet, film coated	.5 mg	Current	Unavailable	Manufacturing	11/08/2025
esomeprazole	Capsule, enteric	20 mg	Resolved	Available	Manufacturing	11/08/2025
celecoxib	Capsule, hard	100 mg	Current	Unavailable	Manufacturing	11/08/2025
alprazolam	Tablet, uncoated	2 mg	Resolved	Available	Manufacturing	11/08/2025
rifampicin	Capsule, hard	300 mg	Current	Limited Availability	Manufacturing	11/08/2025

2025.08.18 [ 米国 ]

ASHP供給不足情報（2025年8月11日～8月17日）

Generic Name	Shortage Status	Revision Date	Created Date
Imatinib Mesylate Tablets	Current Shortages	15-Aug-25	14-May-25
Lidocaine with Epinephrine Injection	Current Shortages	15-Aug-25	25-Jun-15
Liraglutide Injection	Current Shortages	15-Aug-25	20-Jul-23
Minoxidil 2.5 mg Tablets	Current Shortages	15-Aug-25	28-Nov-23
Ribavirin Inhalation	Current Shortages	15-Aug-25	23-May-23
Cefdinir Oral Presentations	Current Shortages	14-Aug-25	29-Jun-23
Dimenhydrinate Injection	Current Shortages	14-Aug-25	14-Aug-25
Heparin Lock Flush Syringes	Resolved Shortages	14-Aug-25	18-Dec-24
Lidocaine Injection	Current Shortages	14-Aug-25	23-Jun-15
Lorazepam Tablets	Current Shortages	14-Aug-25	4-Oct-18
Mometasone Furoate Aerosol for Oral Inhalation	Current Shortages	14-Aug-25	29-Jul-25
Morphine Sulfate Extended-Release Tablets	Current Shortages	14-Aug-25	12-Dec-24
Morphine Sulfate Immediate-Release Tablets	Current Shortages	14-Aug-25	6-Apr-25
Acetaminophen Injection	Current Shortages	13-Aug-25	12-Mar-25
Adenosine Injection	Current Shortages	13-Aug-25	3-Apr-23
Dextran Low Molecular Weight (Dextran 40), 10% Injection	Current Shortages	13-Aug-25	13-Aug-25
Pyridostigmine Bromide Extended-Release Tablets	Current Shortages	13-Aug-25	7-Feb-25
Remifentanil Injection	Current Shortages	13-Aug-25	22-Jun-22
Valproate Sodium Injection	Current Shortages	13-Aug-25	13-Aug-25
Atropine Sulfate Injection	Current Shortages	12-Aug-25	8-Jun-15
Dexmedetomidine Hydrochloride 100 mcg/mL Vials for Injection	Current Shortages	12-Aug-25	3-Jul-24
Dexmedetomidine Hydrochloride 4 mcg/mL Premix for Injection	Current Shortages	12-Aug-25	2-Jun-25
Leucovorin Calcium Injection	Current Shortages	12-Aug-25	2-Jun-15
Lorazepam Injection	Current Shortages	12-Aug-25	23-Jun-15
Mesna Injection	Resolved Shortages	12-Aug-25	21-Feb-24
Metoprolol Injection	Current Shortages	12-Aug-25	7-Nov-17
Metronidazole Hydrochloride Injection	Current Shortages	12-Aug-25	20-Oct-21
Midazolam Injection	Current Shortages	12-Aug-25	14-Jun-19
Morphine Injection	Current Shortages	12-Aug-25	3-Jun-15
Nalbuphine Injection	Current Shortages	12-Aug-25	8-Nov-22
Orphenadrine Citrate Injection	Resolved Shortages	12-Aug-25	16-Jul-24
Phenytoin Sodium Injection	Current Shortages	12-Aug-25	20-Dec-22
Propofol Emulsion Injection	Current Shortages	12-Aug-25	2-Apr-20
Sodium Bicarbonate Injection	Current Shortages	12-Aug-25	17-Feb-17

2025.08.18 [ 米国 ]
FDA供給不足情報：新規・更新（2025年8月11日～8月17日）
New
August 15, 2025
- Celecoxib Capsule (Discontinuation)
August 13, 2025
- Palivizumab Injection (Discontinuation)
August 12, 2025
- Desipramine Hydrochloride Tablet (Discontinuation)
Updated
August 15, 2025
- Cromolyn Sodium Concentrate (Currently In Shortage)
August 11, 2025
- Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection (Currently In Shortage)
- Dexamethasone Sodium Phosphate Injection (Currently In Shortage)
- Dextrose Monohydrate 10% Injection (Currently In Shortage)
- Fentanyl Citrate Injection (Currently In Shortage)
- Hydromorphone Hydrochloride Injection (Currently In Shortage)
- Morphine Sulfate Injection (Currently In Shortage)
- Rocuronium Bromide Injection (Currently In Shortage)
- Sodium Bicarbonate Injection (Currently In Shortage)