更新された供給不足状況を示しています。
ある時点での供給不足の全体的状況は「供給関連情報」に定期的にアップします。
米国
- 2025.01.13
- 2025.01.13
January 10, 2025
- Bupivacaine Hydrochloride Injection (Discontinuation)
- Ethinyl Estradiol; Norethindrone Tablet, Chewable (Discontinuation)
January 8, 2025
- Methotrexate Sodium Injection (Discontinuation)
- Ramelteon Tablet (Discontinuation)
January 6, 2025
- Adalimumab-adbm Injection (Discontinuation)
- Cisatracurium Besylate Injection (Discontinuation)
- Ezetimibe; Simvastatin Tablet (Discontinuation)
- 2025.01.06
Generic Name Shortage Status Revision Date Gadobenate Dimeglumine Injection Current Shortages 3-Jan-25 Lisdexamfetamine Dimesylate Capsules Current Shortages 3-Jan-25 Oseltamivir Oral Suspension and Capsules Current Shortages 3-Jan-25 Dexmedetomidine Hydrochloride 100 mcg/mL Vials for Injection Current Shortages 2-Jan-25 Magnesium Sulfate Injection Current Shortages 2-Jan-25 Furosemide Injection Current Shortages 31-Dec-24 Magnesium Citrate Oral Solution Current Shortages 31-Dec-24 Lanreotide Acetate Injection Current Shortages 30-Dec-24 Lidocaine Injection Current Shortages 30-Dec-24 Theophylline 24-Hour Extended Release Capsules and Tablets Current Shortages 30-Dec-24 - 2025.01.06
January 3, 2025
- Lisdexamfetamine Dimesylate Capsule (Currently In Shortage)
カナダ
カナダの情報はありません。
オーストラリア
- 2025.01.13
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated cytarabine Injection, solution 100 mg Resolved Available Unexpected increase in consumer demand 10/01/2025 topiramate Tablet, film coated 100 mg Resolved Available Manufacturing 10/01/2025 topiramate Tablet, film coated 200 mg Resolved Available Manufacturing 10/01/2025 levetiracetam Tablet, film coated 500 mg Resolved Available Manufacturing 10/01/2025 clonidine hydrochloride Tablet, uncoated 100 microgram Current Unavailable Transport / Logistic issues / Storage capacity issues 10/01/2025 bisoprolol fumarate Tablet 2.5 mg Resolved Available Manufacturing 10/01/2025 azithromycin dihydrate Tablet, film coated 524.05 mg Current Unavailable Manufacturing 10/01/2025 eftrenonacog alfa Injection, powder for 1000 IU Resolved Available Unexpected increase in consumer demand 10/01/2025 eftrenonacog alfa Injection, powder for 250 IU Current Unavailable Unexpected increase in consumer demand 10/01/2025 clopidogrel besilate Tablet, film coated 112.1 mg Current Limited Availability Manufacturing 10/01/2025 clonidine hydrochloride Tablet 100 microgram Current Unavailable Unexpected increase in consumer demand 10/01/2025 clonidine hydrochloride Tablet 100 microgram Current Unavailable Manufacturing 10/01/2025 irbesartan Tablet, film coated 300 mg Resolved Available Manufacturing 10/01/2025 ivabradine hydrochloride Tablet, film coated 8.085 mg Anticipated Available Manufacturing 10/01/2025 mesalazine Tablet, enteric coated 250 mg Current Limited Availability Manufacturing 10/01/2025 risperidone Tablet, film coated .5 mg Resolved Available Manufacturing 10/01/2025 ravulizumab Injection, intravenous infusion 100 mg/mL Resolved Available Transport / Logistic issues / Storage capacity issues 10/01/2025 prucalopride succinate Tablet 2.642 mg Current Unavailable Manufacturing 10/01/2025 thiotepa Injection, powder for 15 mg Resolved Available Unexpected increase in consumer demand 10/01/2025 thiotepa Injection, powder for 15 mg Current Unavailable Commercial Changes / Commercial viability 10/01/2025 estradiol hemihydrate Drug delivery system, transdermal 1.54 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 10/01/2025 doxycycline hyclate Tablet, film coated 57.5 mg Current Limited Availability Manufacturing 10/01/2025 estradiol hemihydrate Drug delivery system, transdermal .77 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 10/01/2025 estradiol hemihydrate Drug delivery system, transdermal 3.09 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 10/01/2025 metformin hydrochloride Tablet, film coated 500 mg Current Unavailable Manufacturing 10/01/2025 estradiol hemihydrate Drug delivery system, transdermal 2.32 mg Current Limited Availability Unexpected increase in demand due to other sponsors unable to supply 10/01/2025 clonidine hydrochloride Tablet, uncoated 150 microgram Current Unavailable Transport / Logistic issues / Storage capacity issues 10/01/2025 famotidine Tablet, film coated 20 mg Current Unavailable Manufacturing 10/01/2025 famotidine Tablet, film coated 40 mg Current Unavailable Manufacturing 10/01/2025 nizatidine Capsule, hard 300 mg Current Limited Availability Manufacturing 10/01/2025 dopamine hydrochloride Injection, concentrated 40 mg/mL Resolved Available Manufacturing 9/01/2025 paroxetine hydrochloride Tablet, film coated 22.21 mg Current Limited Availability Manufacturing 9/01/2025 mesalazine Tablet, enteric coated 800 mg Current Limited Availability Manufacturing 9/01/2025 Trastuzumab Injection, powder for 60 mg Current Unavailable Manufacturing 9/01/2025 naloxone hydrochloride dihydrate Spray, nasal 2.2 mg/actuation Current Limited Availability Manufacturing 9/01/2025 daptomycin Injection, powder for 500 mg Resolved Available Manufacturing 9/01/2025 Adalimumab Injection, solution 40 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 9/01/2025 carbamazepine Tablet, modified release 200 mg Resolved Available Manufacturing 9/01/2025 oxcarbazepine Tablet, film coated 150 mg Resolved Available Manufacturing 9/01/2025 citalopram hydrobromide Tablet, film coated 24.98 mg Current Limited Availability Manufacturing 9/01/2025 Meningococcal polysaccharide group C~Tetanus toxoid Injection, suspension 20 microgram/mL~20 microgram/mL Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 9/01/2025 diclofenac sodium Suppository, moulded 50 mg Resolved Available Transport / Logistic issues / Storage capacity issues 9/01/2025 sevelamer hydrochloride Tablet, film coated 800 mg Resolved Available Manufacturing 8/01/2025 hydrocortisone acetate Eye Ointment 10 mg/g Current Unavailable Manufacturing 8/01/2025 tamsulosin hydrochloride~dutasteride Capsule, modified release 400 microgram~500 microgram Resolved Available Manufacturing 8/01/2025 rosuvastatin calcium~ezetimibe Tablet~Tablet, film coated 20.791 mg~10 mg Resolved Available Manufacturing 8/01/2025 quetiapine fumarate Tablet, film coated 28.78 mg Current Limited Availability Manufacturing 8/01/2025 efmoroctocog alfa Injection, powder for 2000 IU Current Unavailable Unexpected increase in consumer demand 8/01/2025 cisatracurium besilate Injection, solution 14.07 mg Current Unavailable Transport / Logistic issues / Storage capacity issues 8/01/2025 citalopram hydrobromide Tablet, film coated 12.495 mg Current Unavailable Manufacturing 8/01/2025 buprenorphine Drug delivery system, transdermal 5 mg Current Limited Availability Manufacturing 8/01/2025 isotretinoin Capsule, soft 10 mg Current Unavailable Manufacturing 8/01/2025 olmesartan medoxomil~hydrochlorothiazide Tablet 20 mg~12.5 mg Current Unavailable Manufacturing 8/01/2025 hydrochlorothiazide~olmesartan medoxomil Tablet 25 mg~40 mg Current Limited Availability Manufacturing 8/01/2025 Trastuzumab Injection, powder for 150 mg Current Unavailable Manufacturing 8/01/2025 clobazam Tablet, uncoated 10 mg Current Unavailable Manufacturing 8/01/2025 oxaliplatin Injection, concentrated 100 mg Current Limited Availability Manufacturing 8/01/2025 reboxetine mesilate Tablet, uncoated 5.224 mg Anticipated Available Manufacturing 8/01/2025 ethosuximide Capsule, soft 250 mg Discontinued Unavailable Manufacturing 8/01/2025 acetylcysteine Injection, concentrated 2 g Current Unavailable Manufacturing 7/01/2025 fentanyl Drug delivery system, transdermal 2.1 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 7/01/2025 tramadol hydrochloride Tablet, modified release 200 mg Current Limited Availability Manufacturing 7/01/2025 bisoprolol fumarate Tablet 5 mg Resolved Available Manufacturing 7/01/2025 duloxetine hydrochloride Capsule, enteric 33.65 mg Current Limited Availability Manufacturing 7/01/2025 bortezomib Injection, powder for 3.5 mg Current Limited Availability Manufacturing 7/01/2025 amlodipine besilate Tablet 6.93 mg Current Limited Availability Manufacturing 7/01/2025 doxylamine succinate~codeine phosphate hemihydrate~paracetamol Tablet, uncoated 5.1 mg~10 mg~500 mg Resolved Available Manufacturing 7/01/2025 cefuroxime axetil Tablet, film coated 300.715 mg Current Limited Availability Manufacturing 7/01/2025 ezetimibe Tablet 10 mg Resolved Available Unexpected increase in consumer demand 7/01/2025 tadalafil Tablet, film coated 5 mg Resolved Available Manufacturing 7/01/2025 tadalafil Tablet, film coated 20 mg Resolved Available Manufacturing 7/01/2025 amlodipine besilate~olmesartan medoxomil Tablet, film coated 6.935 mg~40 mg Current Unavailable Manufacturing 7/01/2025 dexmedetomidine hydrochloride Injection, concentrated 118 microgram/mL Resolved Available Manufacturing 7/01/2025 dimethyl fumarate Capsule, enteric 120 mg Current Limited Availability Manufacturing 7/01/2025 metoprolol succinate Tablet, modified release 23.75 mg Current Limited Availability Manufacturing 7/01/2025 lanreotide acetate Injection, solution 133.33 mg Resolved Available Transport / Logistic issues / Storage capacity issues 7/01/2025 lanreotide acetate Injection, solution 100 mg Resolved Available Transport / Logistic issues / Storage capacity issues 7/01/2025 sitagliptin hydrochloride monohydrate Tablet, film coated 109 mg Current Unavailable Manufacturing 7/01/2025 sitagliptin hydrochloride monohydrate Tablet, film coated 54.5 mg Current Unavailable Manufacturing 7/01/2025 sitagliptin hydrochloride monohydrate Tablet, film coated 27.25 mg Current Unavailable Manufacturing 7/01/2025 paracetamol Tablet, modified release 665 mg Current Limited Availability Transport / Logistic issues / Storage capacity issues 7/01/2025 heparin sodium Injection, solution 5000 IU/mL Resolved Available Manufacturing 7/01/2025 methylphenidate hydrochloride Capsule, modified release 30 mg Resolved Available Manufacturing 7/01/2025 gabapentin Tablet, film coated 800 mg Current Unavailable Manufacturing 6/01/2025 quetiapine fumarate Tablet, film coated 28.78 mg Resolved Available Manufacturing 6/01/2025 quetiapine fumarate Tablet, film coated 345.36 mg Resolved Available Manufacturing 6/01/2025 adefovir dipivoxil Tablet 10 mg Resolved Available Unexpected increase in consumer demand 6/01/2025 ezetimibe Tablet, uncoated 10 mg Resolved Available Unexpected increase in demand due to other sponsors unable to supply 6/01/2025 apomorphine hydrochloride hemihydrate Injection, solution 10 mg Resolved Available Manufacturing 6/01/2025 lurasidone hydrochloride Tablet, film coated 80 mg Current Unavailable Manufacturing 6/01/2025 furosemide Injection, solution 10 mg/mL Current Limited Availability Transport / Logistic issues / Storage capacity issues 6/01/2025 rosuvastatin calcium~ezetimibe Tablet 10.4 mg~10 mg Current Unavailable Manufacturing 6/01/2025 ezetimibe~rosuvastatin calcium Tablet~Tablet, film coated 10 mg~41.6 mg Current Unavailable Manufacturing 6/01/2025 tamoxifen citrate Tablet, uncoated 30.4 mg Discontinued Reduction in supply until supply is exhausted Commercial Changes / Commercial viability 6/01/2025 cabergoline Tablet, uncoated 1 mg Anticipated Available Manufacturing 6/01/2025 - 2025.01.06
Active ingredients Dosage form Quantity of active ingredients Shortage status Availability Reason Last updated paclitaxel Injection, concentrated 6 mg/mL Current Limited Availability Manufacturing 3/01/2025 galantamine hydrobromide Capsule, modified release 10.252 mg Anticipated Available Manufacturing 3/01/2025 galantamine hydrobromide Capsule, modified release 30.756 mg Current Limited Availability Manufacturing 3/01/2025 galantamine hydrobromide Capsule, modified release 20.504 mg Current Unavailable Manufacturing 3/01/2025 azithromycin dihydrate Tablet, film coated 524.05 mg Current Limited Availability Manufacturing 3/01/2025 buprenorphine Drug delivery system, transdermal 5 mg Current Limited Availability Manufacturing 3/01/2025 linezolid Tablet, film coated 600 mg Anticipated Available Manufacturing 3/01/2025 azithromycin dihydrate Tablet, film coated 524 mg Current Limited Availability Manufacturing 3/01/2025 fluorouracil Injection, solution 50 mg/mL Current Unavailable Manufacturing 3/01/2025 cisplatin Injection, concentrated 1 mg/mL Current Unavailable Unexpected increase in consumer demand 3/01/2025 potassium chloride Injection, concentrated 75 mg/mL Current Unavailable Commercial Changes / Commercial viability 3/01/2025 mesalazine Tablet, enteric coated 1.6 g Current Limited Availability Manufacturing 3/01/2025 Fremanezumab Injection, solution 225 mg Resolved Available Unexpected increase in consumer demand 3/01/2025 sitagliptin fumarate Tablet, film coated 32.124 mg Current Unavailable Manufacturing 3/01/2025 azithromycin dihydrate Tablet, film coated 524 mg Current Unavailable Unexpected increase in consumer demand 3/01/2025 rifabutin Capsule, hard 150 mg Resolved Available Transport / Logistic issues / Storage capacity issues 3/01/2025 aciclovir Injection, solution 25 mg/mL Resolved Available Manufacturing 3/01/2025 azithromycin dihydrate Tablet, film coated 628.93 mg Resolved Available Manufacturing 3/01/2025 fluticasone propionate Inhalation, pressurised 125 microgram/actuation Current Limited Availability Unexpected increase in consumer demand 3/01/2025 estradiol~dydrogesterone Tablet, film coated 2 mg~10 mg Anticipated Available Manufacturing 3/01/2025 pioglitazone hydrochloride Tablet, uncoated 33.06 mg Anticipated Available Manufacturing 3/01/2025 morphine sulfate pentahydrate Tablet, modified release 10 mg Current Unavailable Manufacturing 2/01/2025 morphine sulfate pentahydrate Tablet, modified release 30 mg Current Unavailable Manufacturing 2/01/2025 morphine sulfate pentahydrate Tablet, modified release 60 mg Current Unavailable Manufacturing 2/01/2025 morphine sulfate pentahydrate Tablet, modified release 100 mg Current Unavailable Manufacturing 2/01/2025 venlafaxine Capsule, modified release 75 mg Resolved Available Manufacturing 2/01/2025 venlafaxine Capsule, modified release 150 mg Resolved Available Manufacturing 2/01/2025 metronidazole Tablet, uncoated 400 mg Anticipated Available Manufacturing 2/01/2025 candesartan cilexetil Tablet, uncoated 4 mg Current Limited Availability Manufacturing 2/01/2025 morphine hydrochloride trihydrate Injection, solution 10 mg/mL Current Limited Availability Manufacturing 2/01/2025 pemetrexed disodium Injection, powder for 110.28 mg Current Unavailable Manufacturing 2/01/2025 pemetrexed disodium Injection, powder for 551.4 mg Current Limited Availability Manufacturing 2/01/2025 pemetrexed disodium Injection, powder for 1102.8 mg Current Unavailable Manufacturing 2/01/2025 betahistine dihydrochloride Tablet 24 mg Resolved Available Unexpected increase in consumer demand 2/01/2025 nebivolol hydrochloride Tablet 10.9 mg Anticipated Available Manufacturing 2/01/2025 ropinirole hydrochloride Tablet, film coated .285 mg Resolved Available Manufacturing 2/01/2025 risperidone Tablet, film coated .5 mg Anticipated Available Manufacturing 2/01/2025 levothyroxine sodium Tablet .05 mg Current Unavailable Manufacturing 2/01/2025 levothyroxine sodium Tablet .2 mg Current Limited Availability Manufacturing 2/01/2025 levothyroxine sodium Tablet .1 mg Current Unavailable Manufacturing 2/01/2025 fentanyl citrate Injection, solution 157 microgram Current Unavailable Manufacturing 2/01/2025 levothyroxine sodium Tablet 50 microgram Resolved Available Manufacturing 2/01/2025 melatonin Capsule, hard 5 mg Resolved Available Unexpected increase in consumer demand 2/01/2025 melatonin Oral Liquid, solution 1 mg/mL Resolved Available Unexpected increase in consumer demand 2/01/2025 riboflavine sodium phosphate~folic acid~sodium pantothenate~Biotin~pyridoxine hydrochloride~cyanocobalamin~sodium ascorbate~nicotinamide~thiamine nitrate Injection, powder for 4.9 mg~.4 mg~16.5 mg~60 microgram~4.9 mg~5 microgram~113 mg~40 mg~3.1 mg Resolved Available Manufacturing 2/01/2025 imipramine hydrochloride Tablet, sugar coated 25 mg Current Unavailable Manufacturing 2/01/2025
ドイツ
- 2025.01.13
Active ingredients Type of reason Message type Date of the last message Ezetimibe; Simvastatin Production problem Change notification 10.01.2025 Hydromorphone hydrochloride Other Change notification 10.01.2025 Trazodone hydrochloride Other Change notification 10.01.2025 Linezolid Production problem Change notification 10.01.2025 Galantamine hydrobromide Production problem Change notification 10.01.2025 Atomoxetine hydrochloride Production problem Change notification 10.01.2025 Quetiapine fumarate (Ph.Eur.) Production problem Change notification 10.01.2025 Rizatriptan benzoate Production problem Change notification 10.01.2025 Fluticasone propionate (Ph.Eur.) Other Change notification 09.01.2025 Etoposide Other Change notification 09.01.2025 Melperone hydrochloride Other Change notification 09.01.2025 Methylphenidate hydrochloride Production problem Change notification 09.01.2025 Buspirone hydrochloride Other Change notification 09.01.2025 Phenoxymethylpenicillin potassium Other Change notification 09.01.2025 Trihexyphenidyl hydrochloride Production problem Change notification 09.01.2025 Doxycycline monohydrate Other Change notification 09.01.2025 Calcium folinate Other Change notification 09.01.2025 Ciprofloxacin hydrochloride (1:1) 1 H<2>O Other Change notification 09.01.2025 Oxycodone hydrochloride (Ph.Eur.) Other Change notification 08.01.2025 Hydromorphone hydrochloride Other Change notification 08.01.2025 Buprenorphine Other Change notification 08.01.2025 Salbutamol sulfate Other Change notification 07.01.2025 Methylphenidate hydrochloride Other Change notification 07.01.2025 Quetiapine fumarate (Ph.Eur.) Other Change notification 07.01.2025 Progesterone Production problem Change notification 06.01.2025 - 2025.01.06
Active ingredients Type of reason Message type Date of the last message Calcium folinate hydrate Other Change notification 03.01.2025 Timolol maleate Production problem Initial notification 03.01.2025 Proxymetacaine hydrochloride Production problem Initial notification 03.01.2025 Hydrocortisone acetate (Ph.Eur.) Production problem Initial notification 03.01.2025 Phenylephrine hydrochloride Production problem Initial notification 03.01.2025 Prednisolone acetate Production problem Initial notification 03.01.2025 Acyclovir Production problem Change notification 03.01.2025 Fluorometholone Production problem Change notification 03.01.2025 Timolol maleate Production problem Change notification 03.01.2025 Morphine sulphate (Ph.Eur.) Other Initial notification 30.12.2024
フランス
- 2025.01.13
Ingredients Status Update Specialty cilastatin sodium, imipenem monohydrate, rebactam monohydrate Supply tension 10-Jan-25 Recarbrio 500 mg/500 mg/250 mg, powder for solution for infusion – acetazolamide Supply tension 10-Jan-25 Diamox 250 mg, scored tablet – paclitaxel Supply tension Jan. 10, 2025 Paclitaxel AHCL 6 mg/ml, dilutable solution for infusion – 100 ml bottle – dexrazoxane hydrochloride Out of stock 10-Jan-25 Savene 20 mg/ml, powder and solvent for solution to be diluted for infusion – lenalidomide Supply voltage Jan. 10, 2025 Lenalidomide Mylan, capsule – nab paclitaxel Supply tension Jan. 9, 2025 Pazenir 5 mg/mL, powder for dispersal by infusion – cyanocobalamin Supply tension Jan. 9, 2025 Vitamin B12 Delagrange 1000 micrograms/2 ml, solution for injection (IM) and oral use – sodium fluorescein Availability Jan. 8, 2025 Fluorescein Faure 0.5%, eye drops solution in single-dose container – peginterferon alfa-2a Supply tension Jan. 7, 2025 Pegasys 90 micrograms, 135 micrograms and 180 micrograms solution for injection in pre-filled syringes – latanoprost Availability Jan. 7, 2025 Monoprost 50 micrograms/ml, eye drops solution in single-dose container – - 2025.01.06
Status Update Ingredients Specialty Out of stock Jan. 3, 2025 ondansetron Zophren 2 mg/ml, solution for injection in ampoule (IV) (box 1 ampoule of 4 ml) – Supply tension Jan. 3, 2025 bevacizumab Aybintio 25 mg/ml, solution to be diluted for infusion (16 ml bottle) – Availability Jan. 2, 2025 somatropin Norditropin Flexpro 5 mg/1.5 ml, solution for injection in pre-filled pen – Supply tension Jan. 2, 2025 peginterferon alfa-2a Pegasys 90 micrograms, 135 micrograms and 180 micrograms solution for injection in pre-filled syringe – Out of stock 31-Dec-24 carmustine Gliadel 7.7 mg, implant – Supply tension 31-Dec-24 somatotropin Genotonorm 12 mg, powder and solvent for solution for injection box of 5 cartridges in GoQuick pre-filled pen – Supply tension Dec. 31, 2024 ondansetron Ondansetron Viatris 2 mg/ml, solution for injection (I.V.) – Out of stock Dec. 30, 2024 fluorouracil Fluorouracil Teva 50 mg/ml, solution for diluted infusion, 100 ml bottle – Remise à disposition Dec. 30, 2024 captopril Noyada 25 mg/5 ml, oral solution – Supply tension Dec. 30, 2024 basiliximab (mammal/mouse/Sp2/O) Simulect 20 mg, powder and solvent for solution for injection or infusion – Supply tension Dec. 30, 2024 tropicamide Mydriaticum 2 mg/0.4 ml, eye drops in single-dose container –
英国
英国の情報はありません。
EU
- 2025.01.15
Prescribing and ordering available pancreatic enzyme replacement therapies (Last updated 9 January 2025)
Update: Each Integrated Care Board (ICB) should have a local management plan to ensure patients are not left without pancreatic enzyme replacement therapies（PERT）. This may include a centralised route to obtain unlicensed imports. Refer to your local ICB to find out if a centralised route is available.